Literature DB >> 993105

The description and antibiotic production of Streptomyces hygroscopicus var. Geldanus.

C BeBoer, A Dietz.   

Abstract

A new variety of Streptomyces hygroscopicus was isolated from a Kalamazoo soil. This isolate is described and identified as var. geldanus. When fermented in preferential media it produces geldanamycin, nigericin, nocardamine, and a libanamycin-like activity. Fermentation conditions, chromatographic separation, and antimicrobial spectra of the antibiotics are given.

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Year:  1976        PMID： 993105     DOI： 10.7164/antibiotics.29.1182

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  9 in total

Review 1.  Geldanamycin: the prototype of a class of antitumor drugs targeting the heat shock protein 90 family of molecular chaperones.

Authors:  H J Ochel; K Eichhorn; G Gademann
Journal:  Cell Stress Chaperones       Date:  2001-04       Impact factor: 3.667

Review 2.  Metagenomic approaches to natural products from free-living and symbiotic organisms.

Authors:  Sean F Brady; Luke Simmons; Jeffrey H Kim; Eric W Schmidt
Journal:  Nat Prod Rep       Date:  2009-09-16       Impact factor: 13.423

3.  Urban park soil microbiomes are a rich reservoir of natural product biosynthetic diversity.

Authors:  Zachary Charlop-Powers; Clara C Pregitzer; Christophe Lemetre; Melinda A Ternei; Jeffrey Maniko; Bradley M Hover; Paula Y Calle; Krista L McGuire; Jeanne Garbarino; Helen M Forgione; Sarah Charlop-Powers; Sean F Brady
Journal:  Proc Natl Acad Sci U S A       Date:  2016-11-28       Impact factor: 11.205

Review 4.  Molecular chaperones in pathogen virulence: emerging new targets for therapy.

Authors:  Len Neckers; Utpal Tatu
Journal:  Cell Host Microbe       Date:  2008-12-11       Impact factor: 21.023

Review 5.  NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinones.

Authors:  David Siegel; Chao Yan; David Ross
Journal:  Biochem Pharmacol       Date:  2011-12-24       Impact factor: 6.100

6.  Structural determination of three different series of compounds as Hsp90 inhibitors using 3D-QSAR modeling, molecular docking and molecular dynamics methods.

Authors:  Jianling Liu; Fangfang Wang; Zhi Ma; Xia Wang; Yonghua Wang
Journal:  Int J Mol Sci       Date:  2011-01-30       Impact factor: 5.923

7.  Nigericin and Geldanamycin Are Phytotoxic Specialized Metabolites Produced by the Plant Pathogen Streptomyces sp. 11-1-2.

Authors:  Gustavo A Díaz-Cruz; Jingyu Liu; Kapil Tahlan; Dawn R D Bignell
Journal:  Microbiol Spectr       Date:  2022-02-28

8.  Hsp-90 and the biology of nematodes.

Authors:  Nik A I I N Him; Victoria Gillan; Richard D Emes; Kirsty Maitland; Eileen Devaney
Journal:  BMC Evol Biol       Date:  2009-10-22       Impact factor: 3.260

9.  A new nematicidal compound produced by Streptomyces albogriseolus HA10002.

Authors:  Qingfei Zeng; Huiqin Huang; Jun Zhu; Zhe Fang; Qianguang Sun; Shixiang Bao
Journal:  Antonie Van Leeuwenhoek       Date:  2013-02-27       Impact factor: 2.271
  9 in total

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