Literature DB >> 9929322

A randomized controlled trial of automated term composition.

P L Elkin1, K R Bailey, C G Chute.   

Abstract

OBJECTIVE: To compare the ability of an Automated Term Composition (ATC) algorithm with non-compositional mappings to provide coverage (exact mappings to a controlled vocabulary) for a randomly selected set of free text entries which were entered as headings to the Impression section of the clinical notes system at the Mayo Foundation. We also compare the results of four evaluators to determine the inter-observer variability and the variance between term sets, with respect to the accuracy of the mappings and the reliability of the failure analysis.
METHODS: From a corpus of approximately 1,000,000 unique terms entered into the Impression/Report/Plan section of the clinical notes system in the calendar year 1997, we randomly selected 1,000 terms. We then further randomized these 1,000 terms into two groups of 500 (Sets A and B). We constructed two copies of the same term matching interface, one without ATC (alpha) and one with ATC (beta). We took four expert Indexers and assigned them to one of the following tasks. The first reviewer (R1) compared set A using the alpha program and then set B using the beta program (R1(Aalpha + Bbeta)). The second compared set A using the alpha program and then set B using the alpha program (R2(A + B) alpha). The third compared set B using the beta program and then set A using the beta program (R3(B + A) beta). The fourth compared set A using the beta program and then set B using the alpha program (R4(Abeta + Balpha)).
RESULTS: The program with Automated Term Composition mapped 540 out of the 1,000 Concepts correctly (54.0%). The same program without ATC mapped only 276 out of the 1,000 Concepts correctly (27.6%). Therefore the program with ATC was significantly more effective at matching concepts in our problem lists than the same search engine without ATC (p < 0.0001; McNemar Method). These figures result from the comparison of the alpha program with the beta program by reviewers one and four. Failure analysis showed that with the alpha version 425 out of the 724 mismatches were because a base concept was missing from the retrieval set (58.7%) and 299 mismatches were from missing qualifiers or modifiers or both (41.3%). In the beta version of the program (with ATC) 340 out of the 460 mismatches were secondary to there being a missing base concept in the retrieval set (73.9%) and only 120 mismatches due to missing modifiers and or qualifiers (26.1%).
CONCLUSIONS: Automated term composition provided significantly better coverage of a randomly chosen set of patient problems, diagnosed at the Mayo Clinic during the 1997 calendar year, when compared with the same information retrieval system without ATC. We believe that these results speak further to the excellent content coverage provided by the UMLS metathesaurus. These authors believe that increased structure, normalization of UMLS content and semantics, and better tools to make use of the currently available content such as automated term composition, are what is needed to leverage the production of commercially viable tools that provide access to controlled vocabularies for medicine.

Entities:  

Mesh:

Year:  1998        PMID: 9929322      PMCID: PMC2232145     

Source DB:  PubMed          Journal:  Proc AMIA Symp        ISSN: 1531-605X


  12 in total

1.  Natural language processing and semantical representation of medical texts.

Authors:  R H Baud; A M Rassinoux; J R Scherrer
Journal:  Methods Inf Med       Date:  1992-06       Impact factor: 2.176

2.  As we may think: the concept space and medical hypertext.

Authors:  J J Cimino; P L Elkin; G O Barnett
Journal:  Comput Biomed Res       Date:  1992-06

3.  A schematic analysis of the Unified Medical Language System.

Authors:  Y Yang; C G Chute
Journal:  Proc Annu Symp Comput Appl Med Care       Date:  1991

4.  Adding your terms and relationships to the UMLS Metathesaurus.

Authors:  M S Tuttle; D D Sherertz; M S Erlbaum; W D Sperzel; L F Fuller; N E Olson; S J Nelson; J J Cimino; C G Chute
Journal:  Proc Annu Symp Comput Appl Med Care       Date:  1991

5.  Cognitive evaluation of the user interface and vocabulary of an outpatient information system.

Authors:  A Kushniruk; V Patel; J J Cimino; R A Barrows
Journal:  Proc AMIA Annu Fall Symp       Date:  1996

6.  Knowledge-based approaches to the maintenance of a large controlled medical terminology.

Authors:  J J Cimino; P D Clayton; G Hripcsak; S B Johnson
Journal:  J Am Med Inform Assoc       Date:  1994 Jan-Feb       Impact factor: 4.497

7.  Toward a medical-concept representation language. The Canon Group.

Authors:  D A Evans; J J Cimino; W R Hersh; S M Huff; D S Bell
Journal:  J Am Med Inform Assoc       Date:  1994 May-Jun       Impact factor: 4.497

8.  The Unified Medical Language System.

Authors:  D A Lindberg; B L Humphreys; A T McCray
Journal:  Methods Inf Med       Date:  1993-08       Impact factor: 2.176

9.  The GALEN project.

Authors:  A L Rector; W A Nowlan
Journal:  Comput Methods Programs Biomed       Date:  1994-10       Impact factor: 5.428

10.  Standardized problem list generation, utilizing the Mayo canonical vocabulary embedded within the Unified Medical Language System.

Authors:  P L Elkin; D N Mohr; M S Tuttle; W G Cole; G E Atkin; K Keck; T B Fisk; B H Kaihoi; K E Lee; M C Higgins; H J Suermondt; N Olson; P L Claus; P C Carpenter; C G Chute
Journal:  Proc AMIA Annu Fall Symp       Date:  1997
View more
  18 in total

1.  Desiderata for a clinical terminology server.

Authors:  C G Chute; P L Elkin; D D Sherertz; M S Tuttle
Journal:  Proc AMIA Symp       Date:  1999

2.  A large-scale evaluation of terminology integration characteristics.

Authors:  F S McDonald; C G Chute; P V Ogren; D Wahner-Roedler; P L Elkin
Journal:  Proc AMIA Symp       Date:  1999

3.  A randomized controlled trial of concept based indexing of Web page content.

Authors:  P L Elkin; A Ruggieri; L Bergstrom; B A Bauer; M Lee; P V Ogren; C G Chute
Journal:  Proc AMIA Symp       Date:  2000

4.  UMLS concept indexing for production databases: a feasibility study.

Authors:  F S McDonald; P L Elkin
Journal:  J Am Med Inform Assoc       Date:  2001 Sep-Oct       Impact factor: 4.497

5.  The horizontal and vertical nature of patient phenotype retrieval: new directions for clinical text processing.

Authors:  Christopher G Chute
Journal:  Proc AMIA Symp       Date:  2002

6.  Coverage of oncology drug indication concepts and compositional semantics by SNOMED-CT.

Authors:  Steven H Brown; Brent A Bauer; Dietland L Wahner-Roedler; Peter L Elkin
Journal:  AMIA Annu Symp Proc       Date:  2003

7.  Terminological mapping for high throughput comparative biology of phenotypes.

Authors:  Y A Lussier; J Li
Journal:  Pac Symp Biocomput       Date:  2004

8.  Detection of blood culture bacterial contamination using natural language processing.

Authors:  Michael E Matheny; Fern Fitzhenry; Theodore Speroff; Jacob Hathaway; Harvey J Murff; Steven H Brown; Elliot M Fielstein; Robert S Dittus; Peter L Elkin
Journal:  AMIA Annu Symp Proc       Date:  2009-11-14

9.  A novel hybrid approach to automated negation detection in clinical radiology reports.

Authors:  Yang Huang; Henry J Lowe
Journal:  J Am Med Inform Assoc       Date:  2007-02-28       Impact factor: 4.497

10.  Using SNOMED CT to represent two interface terminologies.

Authors:  S Trent Rosenbloom; Steven H Brown; David Froehling; Brent A Bauer; Dietlind L Wahner-Roedler; William M Gregg; Peter L Elkin
Journal:  J Am Med Inform Assoc       Date:  2008-10-24       Impact factor: 4.497

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.