OBJECTIVE: To evaluate SNOMED-CT 's ability to represent simple and compositional concepts in FDA approved oncology drug indications. METHODS: Oncology drug indications were decomposed into single and compositional concepts. SNOMED-CT's coverage of single concepts and the semantics needed to create compositional concepts were evaluated using automated and manual techniques. RESULTS: SNOMED-CT covered 86.3% of single concepts present in oncology drug indications; 11.3% of indications were covered completely. Coverage was best for concepts describing diseases, anatomy, and patient characteristics. Medications accounted for 50.5% of missing concepts. Excluding drug names, 45.2% of indications were completely represented. SNOMED-CT's semantics completely represented 60.1% of compositional expressions. CONCLUSIONS: SNOMED-CT's overall coverage of the concepts in oncology drug indications was good. Improvements or alternatives are needed for medications and semantics.
OBJECTIVE: To evaluate SNOMED-CT 's ability to represent simple and compositional concepts in FDA approved oncology drug indications. METHODS: Oncology drug indications were decomposed into single and compositional concepts. SNOMED-CT's coverage of single concepts and the semantics needed to create compositional concepts were evaluated using automated and manual techniques. RESULTS: SNOMED-CT covered 86.3% of single concepts present in oncology drug indications; 11.3% of indications were covered completely. Coverage was best for concepts describing diseases, anatomy, and patient characteristics. Medications accounted for 50.5% of missing concepts. Excluding drug names, 45.2% of indications were completely represented. SNOMED-CT's semantics completely represented 60.1% of compositional expressions. CONCLUSIONS: SNOMED-CT's overall coverage of the concepts in oncology drug indications was good. Improvements or alternatives are needed for medications and semantics.
Authors: Michael E Matheny; Fern Fitzhenry; Theodore Speroff; Jacob Hathaway; Harvey J Murff; Steven H Brown; Elliot M Fielstein; Robert S Dittus; Peter L Elkin Journal: AMIA Annu Symp Proc Date: 2009-11-14
Authors: Steven H Brown; Peter L Elkin; Brent A Bauer; Dietlind Wahner-Roedler; Casey S Husser; Zelalem Temesgen; Shawn P Hardenbrook; Elliot M Fielstein; S Trent Rosenbloom Journal: AMIA Annu Symp Proc Date: 2006
Authors: S Trent Rosenbloom; Steven H Brown; David Froehling; Brent A Bauer; Dietlind L Wahner-Roedler; William M Gregg; Peter L Elkin Journal: J Am Med Inform Assoc Date: 2008-10-24 Impact factor: 4.497
Authors: S Trent Rosenbloom; Randolph A Miller; Kevin B Johnson; Peter L Elkin; Steven H Brown Journal: J Am Med Inform Assoc Date: 2007-10-18 Impact factor: 4.497