Literature DB >> 9925542

Diversification of Escherichia coli expressing an SHV-type extended-spectrum beta-lactamase (ESBL) during a hospital outbreak: emergence of an ESBL-hyperproducing strain resistant to expanded-spectrum cephalosporins.

A Pałucha1, B Mikiewicz, M Gniadkowski.   

Abstract

Twelve SHV-type extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli lac mutant isolates were recovered in October 1997 from 11 patients of the neonatal ward in a Warsaw hospital. The outbreak was clonal; however, some of the isolates expressed a much higher level of resistance to several beta-lactam antibiotics, including expanded-spectrum cephalosporins. This phenotype has been attributed to beta-lactamase hyperproduction correlating with the multiplication of ESBL gene copies, as was demonstrated for representative isolates.

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Year:  1999        PMID: 9925542      PMCID: PMC89087     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  17 in total

1.  Nucleotide sequence of the SHV-5 beta-lactamase gene of a Klebsiella pneumoniae plasmid.

Authors:  D Billot-Klein; L Gutmann; E Collatz
Journal:  Antimicrob Agents Chemother       Date:  1990-12       Impact factor: 5.191

2.  An IS1-like element is responsible for high-level synthesis of extended-spectrum beta-lactamase TEM-6 in Enterobacteriaceae.

Authors:  S Goussard; W Sougakoff; C Mabilat; A Bauernfeind; P Courvalin
Journal:  J Gen Microbiol       Date:  1991-12

3.  A new plasmidic cefotaximase from patients infected with Salmonella typhimurium.

Authors:  A Bauernfeind; J M Casellas; M Goldberg; M Holley; R Jungwirth; P Mangold; T Röhnisch; S Schweighart; R Wilhelm
Journal:  Infection       Date:  1992 May-Jun       Impact factor: 3.553

4.  Direct sequencing of the amplified structural gene and promoter for the extended-broad-spectrum beta-lactamase TEM-9 (RHH-1) of Klebsiella pneumoniae.

Authors:  C Mabilat; S Goussard; W Sougakoff; R C Spencer; P Courvalin
Journal:  Plasmid       Date:  1990-01       Impact factor: 3.466

5.  Variations between the nucleotide sequences of Tn1, Tn2, and Tn3 and expression of beta-lactamase in Pseudomonas aeruginosa and Escherichia coli.

Authors:  S T Chen; R C Clowes
Journal:  J Bacteriol       Date:  1987-02       Impact factor: 3.490

6.  Extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns.

Authors:  V Jarlier; M H Nicolas; G Fournier; A Philippon
Journal:  Rev Infect Dis       Date:  1988 Jul-Aug

7.  Synergistic effect of dosage and bacterial inoculum in TEM-1 mediated antibiotic resistance.

Authors:  J A Reguera; F Baquero; J C Perez-Diaz; J L Martinez
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1988-12       Impact factor: 3.267

8.  Multicenter evaluation of arbitrarily primed PCR for typing of Staphylococcus aureus strains.

Authors:  A van Belkum; J Kluytmans; W van Leeuwen; R Bax; W Quint; E Peters; A Fluit; C Vandenbroucke-Grauls; A van den Brule; H Koeleman
Journal:  J Clin Microbiol       Date:  1995-06       Impact factor: 5.948

9.  Two improved promoter sequences for the beta-lactamase expression arising from a single base-pair substitution.

Authors:  S T Chen; R C Clowes
Journal:  Nucleic Acids Res       Date:  1984-04-11       Impact factor: 16.971

10.  Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate.

Authors:  C H O'Callaghan; A Morris; S M Kirby; A H Shingler
Journal:  Antimicrob Agents Chemother       Date:  1972-04       Impact factor: 5.191

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  4 in total

1.  Mosaic structure of p1658/97, a 125-kilobase plasmid harboring an active amplicon with the extended-spectrum beta-lactamase gene blaSHV-5.

Authors:  M Zienkiewicz; I Kern-Zdanowicz; M Gołebiewski; J Zyliñska; P Mieczkowski; M Gniadkowski; J Bardowski; P Cegłowski
Journal:  Antimicrob Agents Chemother       Date:  2007-01-12       Impact factor: 5.191

2.  A novel complex mutant beta-lactamase, TEM-68, identified in a Klebsiella pneumoniae isolate from an outbreak of extended-spectrum beta-lactamase-producing Klebsiellae.

Authors:  J Fiett; A Pałucha; B Miaczyńska; M Stankiewicz; H Przondo-Mordarska; W Hryniewicz; M Gniadkowski
Journal:  Antimicrob Agents Chemother       Date:  2000-06       Impact factor: 5.191

3.  Occurrence and transferability of beta-lactam resistance in Enterobacteriaceae isolated in Children's University Hospital in Bratislava.

Authors:  H Bujdáková; J Hanzen; S Jankovicová; J Klimácková; M Moravcíková; P Milosovic; D Michálková-Papajová; J Kallová; A Jakab; M Kettner
Journal:  Folia Microbiol (Praha)       Date:  2001       Impact factor: 2.099

4.  Molecular epidemiology of Serratia marcescens in two hospitals in Gdańsk, Poland, over a 5-year period.

Authors:  Lukasz Naumiuk; Anna Baraniak; Marek Gniadkowski; Beata Krawczyk; Bartosz Rybak; Ewa Sadowy; Alfred Samet; Józef Kur
Journal:  J Clin Microbiol       Date:  2004-07       Impact factor: 5.948

  4 in total

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