Literature DB >> 9925247

Fractionated high dose rate brachytherapy moulds--a precise treatment for carcinoma of the pinna.

E Allan1, A Stanton, D Pye, C Collins, L Perry, M Filby, J Wilkinson.   

Abstract

BACKGROUND AND
PURPOSE: The aim of this paper is to describe a fractionated high dose rate brachytherapy procedure for the treatment of small superficial cancers of the pinna and to report the outcome in a small series of patients.
MATERIALS AND METHODS: Thirteen patients with superficial cancers of the pinna, not invading cartilage, have been treated and in the majority of cases the tumour thickness was determined by a transdermal ultrasound measurement. For the single-plane moulds the prescribed surface dose was 45 Gy in eight fractions over 5 days and the moulds were constructed such that the full thickness of the disease, as determined by the ultrasound measurement, would lie within the 80% isodose surface. One case was treated with a sandwich mould and in this case the dose was reduced to 42.5 Gy. The treatment machine was a high dose rate microselectron, which contains a single stepping iridium source.
RESULTS: The radiation reactions were of moderate severity, but were limited to the high dose volume. In all cases there was complete tumour resolution and rapid healing occurred leaving a barely perceptible scar. There were no recurrences over a minimum follow-up time of 18 months and there were no late radiation complications in this period.
CONCLUSIONS: The treatment of superficial carcinoma of the pinna by means of HDR moulds is a safe and reliable technique. In this small series of patients there was total tumour control with excellent cosmesis.

Entities:  

Mesh:

Year:  1998        PMID: 9925247     DOI: 10.1016/s0167-8140(98)00059-0

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  7 in total

1.  Radiotherapy treatment of non-melanoma skin cancer: a survey of current UK practice and commentary.

Authors:  A J McPartlin; N J Slevin; A J Sykes; A Rembielak
Journal:  Br J Radiol       Date:  2014-09-05       Impact factor: 3.039

Review 2.  The State of the Art of Radiotherapy for Non-melanoma Skin Cancer: A Review of the Literature.

Authors:  Sofian Benkhaled; Dirk Van Gestel; Carolina Gomes da Silveira Cauduro; Samuel Palumbo; Veronique Del Marmol; Antoine Desmet
Journal:  Front Med (Lausanne)       Date:  2022-06-27

3.  High-dose-rate brachytherapy using Leipzig applicators for non-melanoma localized skin cancer.

Authors:  Antonio Cassio Assis Pellizzon; Ricardo Fogaroli; Michael Jenwey Chen; Polyana Maia; Guilherme Gondim; Douglas de Castro Guedes; Henderson Ramos; Maria Leticia Gobo Silva
Journal:  J Contemp Brachytherapy       Date:  2020-10-30

4.  High-dose-rate (HDR) plesiotherapy with custom-made moulds for the treatment of non-melanoma skin cancer.

Authors:  Angel Montero; Raúl Hernanz; Ana-Belén Capuz; Eva Fernández; Asunción Hervás; Rafael Colmenares; Alfredo Polo; Sonsoles Sancho; Rafael Molerón; Carmen Vallejo; Alfredo Ramos
Journal:  Clin Transl Oncol       Date:  2009-11       Impact factor: 3.405

5.  Non-melanoma skin cancer treated with HDR Valencia applicator: clinical outcomes.

Authors:  Alejandro Tormo; Francisco Celada; Silvia Rodriguez; Rafael Botella; Antonio Ballesta; Michael Kasper; Zoubir Ouhib; Manuel Santos; Jose Perez-Calatayud
Journal:  J Contemp Brachytherapy       Date:  2014-06-03

6.  Clinical outcomes with high-dose-rate surface mould brachytherapy for intra-oral and skin malignancies involving head and neck region.

Authors:  Ashwini Budrukkar; Archya Dasgupta; Prakash Pandit; Sarbani Ghosh Laskar; Vedang Murthy; Ritu Raj Upreti; Tejpal Gupta; Kanchan Dholam; Jai Prakash Agarwal
Journal:  J Contemp Brachytherapy       Date:  2017-03-23

Review 7.  Interventions for non-metastatic squamous cell carcinoma of the skin: systematic review and pooled analysis of observational studies.

Authors:  Louise Lansbury; Fiona Bath-Hextall; William Perkins; Wendy Stanton; Jo Leonardi-Bee
Journal:  BMJ       Date:  2013-11-04
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.