Literature DB >> 25189280

Radiotherapy treatment of non-melanoma skin cancer: a survey of current UK practice and commentary.

A J McPartlin1, N J Slevin, A J Sykes, A Rembielak.   

Abstract

OBJECTIVE: In the ongoing absence of available trial data, a national survey was carried out to provide details on radiotherapy treatment strategy for non-melanoma skin cancer (NMSC).
METHODS: A survey of clinical oncologists treating NMSC was performed. The respondents were asked for basic information on workload as well as a proposed treatment strategy for various clinical scenarios for patients of varying fitness.
RESULTS: A total of 43 completed and 20 partially completed surveys were received. There was a wide variation in the workload and additional disease sites that respondents had responsibility for. Kilovoltage radiotherapy was available to 81% of responders. The respondents' approach was affected by the fitness of patients, with longer fractionation regimes proposed for younger, fitter patients and shorter or non-standard fractionations more likely for the infirm elderly. Four daily fractionation regimes (18-20 Gy in 1 fraction, 35 Gy in 5 fractions, 45 Gy in 10 fractions and 55 Gy in 20 fractions) were most commonly suggested. There was a large degree of variation in non-standard fractions proposed with significant potential differences in radiobiological effect. Concern over the use of kilovoltage photons on skin over cartilage was apparent, as was a reluctance to use radiotherapy in areas of increased risk of poor wound healing.
CONCLUSION: The survey results largely showed practice to be in line with available published evidence. The variation seen in some areas, such as non-standard fractionation, would benefit from the publication of local outcomes to achieve a more consistent approach. ADVANCES IN KNOWLEDGE: This study provides information on national practices and identifies variations, particularly within widespread use of non-standard fractionation.

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Year:  2014        PMID: 25189280      PMCID: PMC4207153          DOI: 10.1259/bjr.20140501

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.039


  37 in total

Review 1.  Radiation therapy in the management of cutaneous malignancies.

Authors:  J R Wong; C C Wang
Journal:  Clin Dermatol       Date:  2001 May-Jun       Impact factor: 3.541

Review 2.  Radiation therapy for Bowen's disease: lessons for lesions of the lower extremity.

Authors:  M T Dupree; R A Kiteley; K Weismantle; R Panos; P A Johnstone
Journal:  J Am Acad Dermatol       Date:  2001-09       Impact factor: 11.527

3.  Results of radiotherapy for epithelial skin cancer of the pinna: the Princess Margaret Hospital experience, 1982-1993.

Authors:  J J Silva; R W Tsang; T Panzarella; W Levin; W Wells
Journal:  Int J Radiat Oncol Biol Phys       Date:  2000-05-01       Impact factor: 7.038

4.  Radiotherapy for epithelial skin cancer.

Authors:  J Locke; S Karimpour; G Young; M A Lockett; C A Perez
Journal:  Int J Radiat Oncol Biol Phys       Date:  2001-11-01       Impact factor: 7.038

5.  Radiotherapy management for squamous cell carcinoma of the nasal skin: the Princess Margaret Hospital experience.

Authors:  May N Tsao; Richard W Tsang; Fei Fei Liu; Tony Panzarella; Lorne Rotstein
Journal:  Int J Radiat Oncol Biol Phys       Date:  2002-03-15       Impact factor: 7.038

6.  Radiotherapy for locally advanced basal cell and squamous cell carcinomas of the skin.

Authors:  Winkle Kwan; Don Wilson; Veronika Moravan
Journal:  Int J Radiat Oncol Biol Phys       Date:  2004-10-01       Impact factor: 7.038

7.  Orthovoltage radiotherapy in the management of medial canthal basal cell carcinoma.

Authors:  Hatem Krema; Evelyn Herrmann; Alisha Albert-Green; David Payne; Normand Laperriere; Caroline Chung
Journal:  Br J Ophthalmol       Date:  2013-03-26       Impact factor: 4.638

8.  [Radiotherapy of carcinomas of the dorsum manus (author's transl)].

Authors:  P Szabó
Journal:  Strahlentherapie       Date:  1981-04

9.  Recurrent basal cell carcinoma. A review concerning the incidence, behavior, and management of recurrent basal cell carcinoma, with emphasis on the incompletely excised lesion.

Authors:  L Koplin; H A Zarem
Journal:  Plast Reconstr Surg       Date:  1980-05       Impact factor: 4.730

10.  Outcome of split-thickness skin grafts after external beam radiotherapy.

Authors:  Duc T Bui; Ashwin Chunilal; Babak J Mehrara; Joseph J Disa; Kaled M Alektiar; Peter G Cordeiro
Journal:  Ann Plast Surg       Date:  2004-06       Impact factor: 1.539

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  5 in total

Review 1.  Electronic brachytherapy--current status and future directions.

Authors:  D J Eaton
Journal:  Br J Radiol       Date:  2015-03-06       Impact factor: 3.039

2.  Excessive applicator radiation leakage for a common therapeutic kilovoltage system.

Authors:  Brad Beeksma; Joerg Lehmann
Journal:  Br J Radiol       Date:  2018-11-15       Impact factor: 3.039

3.  Current status of kilovoltage (kV) radiotherapy in the UK: installed equipment, clinical workload, physics quality control and radiation dosimetry.

Authors:  Antony L Palmer; Michael Pearson; Paul Whittard; Katie E McHugh; David J Eaton
Journal:  Br J Radiol       Date:  2016-10-12       Impact factor: 3.039

4.  Skin surface brachytherapy: A survey of contemporary practice patterns.

Authors:  Anna O Likhacheva; Phillip M Devlin; Shervin M Shirvani; Christopher A Barker; Phillip Beron; Ajay Bhatnagar; Stephen W Doggett; Lawrence Hochman; Charles Hsu; Michael Kasper; Martin Keisch; Subhakar Mutyala; Bradley Prestidge; Silvia Rodriguez Villalba; Vershalee Shukla; Srinath Sundararaman; Mitchell Kamrava
Journal:  Brachytherapy       Date:  2016-11-28       Impact factor: 2.362

5.  A small case series about safety and effectiveness of a hypofractionated electron beam radiotherapy schedule in five fractions for facial non melanoma skin cancer among frail and elderly patients.

Authors:  Gianluca Ferini; Laura Molino; Laura Bottalico; Paolino De Lucia; Francesco Garofalo
Journal:  Rep Pract Oncol Radiother       Date:  2021-02-25
  5 in total

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