Literature DB >> 9916247

Design and characterization of gramicidin channels.

D V Greathouse1, R E Koeppe, L L Providence, S Shobana, O S Andersen.   

Abstract

This article summarizes methods for the chemical synthesis and biophysical characterization of gramicidins with varying sequences and labels. The family of gramicidin channels has developed into a powerful model system for understanding fundamental properties, interactions, and dynamics of proteins and lipids generally, and ion channels specifically, in biological membranes.

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Year:  1999        PMID: 9916247     DOI: 10.1016/s0076-6879(99)94031-4

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN: 0076-6879            Impact factor:   1.600


  34 in total

1.  Desformylgramicidin: a model channel with an extremely high water permeability.

Authors:  S M Saparov; Y N Antonenko; R E Koeppe; P Pohl
Journal:  Biophys J       Date:  2000-11       Impact factor: 4.033

2.  Electrospray ionization-mass spectrometry and tandem mass spectrometry reveal self-association and metal-ion binding of hydrophobic peptides: a study of the gramicidin dimer.

Authors:  Raghu K Chitta; Michael L Gross
Journal:  Biophys J       Date:  2004-01       Impact factor: 4.033

3.  Simultaneous optical and electrical recording of single gramicidin channels.

Authors:  V Borisenko; T Lougheed; J Hesse; E Füreder-Kitzmüller; N Fertig; J C Behrends; G A Woolley; G J Schütz
Journal:  Biophys J       Date:  2003-01       Impact factor: 4.033

4.  Amphiphile regulation of ion channel function by changes in the bilayer spring constant.

Authors:  Jens A Lundbaek; Roger E Koeppe; Olaf S Andersen
Journal:  Proc Natl Acad Sci U S A       Date:  2010-08-16       Impact factor: 11.205

5.  Linear rate-equilibrium relations arising from ion channel-bilayer energetic coupling.

Authors:  Per Greisen; Kevin Lum; Md Ashrafuzzaman; Denise V Greathouse; Olaf S Andersen; Jens A Lundbæk
Journal:  Proc Natl Acad Sci U S A       Date:  2011-07-18       Impact factor: 11.205

6.  Interactions of drugs and amphiphiles with membranes: modulation of lipid bilayer elastic properties by changes in acyl chain unsaturation and protonation.

Authors:  Michael J Bruno; Radda Rusinova; Nicholas J Gleason; Roger E Koeppe; Olaf S Andersen
Journal:  Faraday Discuss       Date:  2013       Impact factor: 4.008

7.  Importance of tensor asymmetry for the analysis of 2H NMR spectra from deuterated aromatic rings.

Authors:  Peter Pulay; Erin M Scherer; Patrick C A van der Wel; Roger E Koeppe
Journal:  J Am Chem Soc       Date:  2005-12-14       Impact factor: 15.419

8.  Helical distortion in tryptophan- and lysine-anchored membrane-spanning alpha-helices as a function of hydrophobic mismatch: a solid-state deuterium NMR investigation using the geometric analysis of labeled alanines method.

Authors:  Anna E Daily; Denise V Greathouse; Patrick C A van der Wel; Roger E Koeppe
Journal:  Biophys J       Date:  2007-09-07       Impact factor: 4.033

9.  Geometry and intrinsic tilt of a tryptophan-anchored transmembrane alpha-helix determined by (2)H NMR.

Authors:  Patrick C A van der Wel; Erik Strandberg; J Antoinette Killian; Roger E Koeppe
Journal:  Biophys J       Date:  2002-09       Impact factor: 4.033

10.  Is there a preferential interaction between cholesterol and tryptophan residues in membrane proteins?

Authors:  Andrea Holt; Rodrigo F M de Almeida; Thomas K M Nyholm; Luís M S Loura; Anna E Daily; Rutger W H M Staffhorst; Dirk T S Rijkers; Roger E Koeppe; Manuel Prieto; J Antoinette Killian
Journal:  Biochemistry       Date:  2008-01-24       Impact factor: 3.162

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