Literature DB >> 9882686

Isolation and characterization of the nikR gene encoding a nickel-responsive regulator in Escherichia coli.

K De Pina1, V Desjardin, M A Mandrand-Berthelot, G Giordano, L F Wu.   

Abstract

Expression of the nickel-specific transport system encoded by the Escherichia coli nikABCDE operon is repressed by a high concentration of nickel. By using random transposon Tn10 insertion, we isolated mutants in which expression of the nik operon became constitutive with respect to nickel. We have identified the corresponding nikR gene which encodes a nickel-responsive regulator. Expression of nikR was partially controlled by Fnr through transcription from the nikA promoter region. In addition, a specific transcription start site for the constitutive expression of nikR was found 51 bp upstream of the nikR gene.

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Year:  1999        PMID： 9882686      PMCID： PMC93426     

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  23 in total

1.  'uidA-antibiotic-resistance cassettes for insertion mutagenesis, gene fusions and genetic constructions.

Authors:  N Bardonnet; C Blanco
Journal:  FEMS Microbiol Lett       Date:  1992-06-15       Impact factor: 2.742

Review 2.  Gene regulation of plasmid- and chromosome-determined inorganic ion transport in bacteria.

Authors:  S Silver; M Walderhaug
Journal:  Microbiol Rev       Date:  1992-03

3.  The nik operon of Escherichia coli encodes a periplasmic binding-protein-dependent transport system for nickel.

Authors:  C Navarro; L F Wu; M A Mandrand-Berthelot
Journal:  Mol Microbiol       Date:  1993-09       Impact factor: 3.501

Review 4.  Iron acquisition in microbial pathogenesis.

Authors:  S M Payne
Journal:  Trends Microbiol       Date:  1993-05       Impact factor: 17.079

Review 5.  Search for molecular mechanisms in the genotoxicity of nickel.

Authors:  F W Sunderman
Journal:  Scand J Work Environ Health       Date:  1993       Impact factor: 5.024

6.  The pKSM710 vector cassette provides tightly regulated lac and T7lac promoters and strategies for manipulating N-terminal protein sequences.

Authors:  S Maneewannakul; K Maneewannakul; K Ippen-Ihler
Journal:  Plasmid       Date:  1994-05       Impact factor: 3.466

7.  Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.

Authors:  H J Sofia; V Burland; D L Daniels; G Plunkett; F R Blattner
Journal:  Nucleic Acids Res       Date:  1994-07-11       Impact factor: 16.971

8.  Nickel deficiency gives rise to the defective hydrogenase phenotype of hydC and fnr mutants in Escherichia coli.

Authors:  L F Wu; M A Mandrand-Berthelot; R Waugh; C J Edmonds; S E Holt; D H Boxer
Journal:  Mol Microbiol       Date:  1989-12       Impact factor: 3.501

9.  The hydC region contains a multi-cistronic operon (nik) involved in nickel transport in Escherichia coli.

Authors:  L F Wu; C Navarro; M A Mandrand-Berthelot
Journal:  Gene       Date:  1991-10-30       Impact factor: 3.688

10.  Chromosomal transformation of Escherichia coli recD strains with linearized plasmids.

Authors:  C B Russell; D S Thaler; F W Dahlquist
Journal:  J Bacteriol       Date:  1989-05       Impact factor: 3.490
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  59 in total

1.  NikR is a ribbon-helix-helix DNA-binding protein.

Authors:  P T Chivers; R T Sauer
Journal:  Protein Sci       Date:  1999-11       Impact factor: 6.725

2.  Negative regulation of the gene for Fe-containing superoxide dismutase by an Ni-responsive factor in Streptomyces coelicolor.

Authors:  H J Chung; J H Choi; E J Kim; Y H Cho; J H Roe
Journal:  J Bacteriol       Date:  1999-12       Impact factor: 3.490

Review 3.  Metalloregulatory proteins: metal selectivity and allosteric switching.

Authors:  Hermes Reyes-Caballero; Gregory C Campanello; David P Giedroc
Journal:  Biophys Chem       Date:  2011-04-05       Impact factor: 2.352

4.  Identification and characterization of the nickel uptake system for urease biogenesis in Streptococcus salivarius 57.I.

Authors:  Yi-Ywan M Chen; Robert A Burne
Journal:  J Bacteriol       Date:  2003-12       Impact factor: 3.490

5.  Geobacter uraniireducens NikR displays a DNA binding mode distinct from other members of the NikR family.

Authors:  Erin L Benanti; Peter T Chivers
Journal:  J Bacteriol       Date:  2010-06-25       Impact factor: 3.490

6.  In vivo recognition of the fecA3 target promoter by Helicobacter pylori NikR.

Authors:  Simona Romagnoli; Francesca Agriesti; Vincenzo Scarlato
Journal:  J Bacteriol       Date:  2011-01-07       Impact factor: 3.490

7.  Nickel-responsive induction of urease expression in Helicobacter pylori is mediated at the transcriptional level.

Authors:  A H van Vliet; E J Kuipers; B Waidner; B J Davies; N de Vries; C W Penn; C M Vandenbroucke-Grauls; M Kist; S Bereswill; J G Kusters
Journal:  Infect Immun       Date:  2001-08       Impact factor: 3.441

8.  NikR-operator complex structure and the mechanism of repressor activation by metal ions.

Authors:  Eric R Schreiter; Sheila C Wang; Deborah B Zamble; Catherine L Drennan
Journal:  Proc Natl Acad Sci U S A       Date:  2006-08-31       Impact factor: 11.205

9.  Acid-induced activation of the urease promoters is mediated directly by the ArsRS two-component system of Helicobacter pylori.

Authors:  Michael Pflock; Simone Kennard; Isabel Delany; Vincenzo Scarlato; Dagmar Beier
Journal:  Infect Immun       Date:  2005-10       Impact factor: 3.441

10.  Glutamate Ligation in the Ni(II)- and Co(II)-Responsive Escherichia coli Transcriptional Regulator, RcnR.

Authors:  Carolyn E Carr; Francesco Musiani; Hsin-Ting Huang; Peter T Chivers; Stefano Ciurli; Michael J Maroney
Journal:  Inorg Chem       Date:  2017-05-18       Impact factor: 5.165
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