Literature DB >> 9882372

Induction of B-cell lymphoma in BALB/c nude mice with an ecotropic, B-tropic helper virus present in the murine AIDS virus stock.

L Tayar1, K Higo, Y Kubo, Y Wang, L M Lu, F Zhang, Y Iwatani, L Wang, T Ono, M Maeda, H Sakai, A Ishimoto.   

Abstract

The pathogenicities of the murine AIDS (MAIDS) virus complex (LP-BM5) and ecotropic helper virus (BM5eco) isolated from the complex to BALB/c nude mice were studied to elucidate the possible role of replication-competent helper virus in inducing the monoclonal outgrowth of lymphoid cells. Neither LP-BM5 nor BM5eco was pathogenic in adult BALB/c nude mice. However, B-cell lymphoma developed with a very high frequency when either virus was inoculated into newborn BALB/c nude (nu/nu) mice. The cells from the B-cell lymphoma were easily transplanted into nude mice. These results suggested that ecotropic helper virus in the MAIDS virus complex plays an important role in inducing the monoclonal outgrowth of lymphoid cells under immunodeficient conditions caused by defective virus.

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Year:  1999        PMID： 9882372      PMCID： PMC103991     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  22 in total

1.  Establishment of a hemopoietic stimulating factor producing murine leukemia cell lines: pathogenesis of granulocytosis in L8313 bearing mice.

Authors:  H Sawada; K Itoh; T Kirikae; H Sakoda; H Tezuka; K Kuribayashi; M Maeda; Y Yoshida; H Uchino; M Hanaoka
Journal:  Leuk Res       Date:  1988       Impact factor: 3.156

2.  Plaque assay techniques for murine leukemia viruses.

Authors:  W P Rowe; W E Pugh; J W Hartley
Journal:  Virology       Date:  1970-12       Impact factor: 3.616

3.  Severe immunodeficiency disease induced by a defective murine leukaemia virus.

Authors:  D C Aziz; Z Hanna; P Jolicoeur
Journal:  Nature       Date:  1989-04-06       Impact factor: 49.962

4.  Retrovirus-induced murine acquired immunodeficiency syndrome: natural history of infection and differing susceptibility of inbred mouse strains.

Authors:  J W Hartley; T N Fredrickson; R A Yetter; M Makino; H C Morse
Journal:  J Virol       Date:  1989-03       Impact factor: 5.103

5.  Defective virus is associated with induction of murine retrovirus-induced immunodeficiency syndrome.

Authors:  S K Chattopadhyay; H C Morse; M Makino; S K Ruscetti; J W Hartley
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

6.  Evolution of B cell lineage lymphomas in mice with a retrovirus-induced immunodeficiency syndrome, MAIDS.

Authors:  S P Klinken; T N Fredrickson; J W Hartley; R A Yetter; H C Morse
Journal:  J Immunol       Date:  1988-02-15       Impact factor: 5.422

7.  Organization of the constant-region gene family of the mouse immunoglobulin heavy chain.

Authors:  A Shimizu; N Takahashi; Y Yaoita; T Honjo
Journal:  Cell       Date:  1982-03       Impact factor: 41.582

8.  Dynamics of lymphocytic subpopulations in Friend leukemia virus-induced leukemia.

Authors:  M Kitagawa; O Matsubara; T Kasuga
Journal:  Cancer Res       Date:  1986-06       Impact factor: 12.701

9.  Functional T lymphocytes are required for a murine retrovirus-induced immunodeficiency disease (MAIDS).

Authors:  D E Mosier; R A Yetter; H C Morse
Journal:  J Exp Med       Date:  1987-06-01       Impact factor: 14.307

10.  Expression and rearrangement of the alpha, beta, and gamma chain genes of the T cell receptor in cloned murine large granular lymphocyte lines. No correlation with the cytotoxic spectrum.

Authors:  K Ikuta; M Hattori; K Wake; S Kano; T Honjo; J Yodoi; N Minato
Journal:  J Exp Med       Date:  1986-08-01       Impact factor: 14.307
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  5 in total

1.  Murine AIDS requires CD154/CD40L expression by the CD4 T cells that mediate retrovirus-induced disease: Is CD4 T cell receptor ligation needed?

Authors:  Wen Li; William R Green
Journal:  Virology       Date:  2006-11-17       Impact factor: 3.616

2.  Myeloid-derived suppressor cells in murine AIDS inhibit B-cell responses in part via soluble mediators including reactive oxygen and nitrogen species, and TGF-β.

Authors:  Jessica L Rastad; William R Green
Journal:  Virology       Date:  2016-09-12       Impact factor: 3.616

3.  The role of CD4 T cells in the pathogenesis of murine AIDS.

Authors:  Wen Li; William R Green
Journal:  J Virol       Date:  2006-06       Impact factor: 5.103

4.  Resistance to Friend murine leukemia virus infection conferred by the Fv-4 gene is recessive but appears dominant from the effect of the immune system.

Authors:  F Zhang; L T Ya; Y Iwatani; K Higo; Y Suzuki; M Tanaka; T Nakahara; T Ono; H Sakai; K Kuribayashi; A Ishimoto
Journal:  J Virol       Date:  2000-07       Impact factor: 5.103

Review 5.  The Role of Myeloid-Derived Suppressor Cells in Viral Infection.

Authors:  Megan A O'Connor; Jessica L Rastad; William R Green
Journal:  Viral Immunol       Date:  2017-01-04       Impact factor: 2.257
  5 in total

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