| Literature DB >> 9873741 |
K Yoshiizumi1, N Seko, N Nishimura, S Ikeda, K Yoshino, H Kondo, K Tanizawa.
Abstract
To find out selective potassium channel openers (PCOs), we synthesized several 3,5-disubstituted phenylcyanoguanidine derivatives and investigated their structure-activity relationships (SAR). As a result, we discovered selective PCOs having 1,1-diethylpropyl group toward antihypertensive activity.Entities:
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Year: 1998 PMID： 9873741 DOI： 10.1016/s0960-894x(98)00625-8
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823