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Literature DB >> 9847216

Expanding the TRANSFAC database towards an expert system of regulatory molecular mechanisms.

T Heinemeyer¹, X Chen, H Karas, A E Kel, O V Kel, I Liebich, T Meinhardt, I Reuter, F Schacherer, E Wingender.

Abstract

TRANSFAC is a database on transcription factors, their genomic binding sites and DNA-binding profiles. In addition to being updated and extended by new features, it has been complemented now by a series of additional database modules. Among them, modules which provide data about signal transduction pathways (TRANSPATH) or about cell types/organs/developmental stages (CYTOMER) are available as well as an updated version of the previously described COMPEL database. The databases are available on the WWW at http://transfac.gbf.de/

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Year: 1999 PMID： 9847216 PMCID： PMC148171 DOI： 10.1093/nar/27.1.318

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

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Cited

78 in total

1. Transcription regulatory regions database (TRRD): its status in 2000.

Authors: N A Kolchanov; O A Podkolodnaya; E A Ananko; E V Ignatieva; I L Stepanenko; O V Kel-Margoulis; A E Kel; T I Merkulova; T N Goryachkovskaya; T V Busygina; F A Kolpakov; N L Podkolodny; A N Naumochkin; I M Korostishevskaya; A G Romashchenko; G C Overton
Journal: Nucleic Acids Res Date: 2000-01-01 Impact factor: 16.971

Expanding the TRANSFAC database towards an expert system of regulatory molecular mechanisms.

1. Transcription regulatory regions database (TRRD): its status in 2000.

2. The eukaryotic promoter database (EPD).

3. TRANSFAC: an integrated system for gene expression regulation.

4. SELEX_DB: an activated database on selected randomized DNA/RNA sequences addressed to genomic sequence annotation.

5. COMPEL: a database on composite regulatory elements providing combinatorial transcriptional regulation.

6. The TRANSFAC system on gene expression regulation.

7. TRANSCompel: a database on composite regulatory elements in eukaryotic genes.

8. Sp1 and Egr1 regulate transcription of the Dmrt1 gene in Sertoli cells.

9. Precocious expression of the Glide/Gcm glial-promoting factor in Drosophila induces neurogenesis.

10. Diverse transcriptional initiation revealed by fine, large-scale mapping of mRNA start sites.