Literature DB >> 9811672

mmr, a Mycobacterium tuberculosis gene conferring resistance to small cationic dyes and inhibitors.

E De Rossi1, M Branzoni, R Cantoni, A Milano, G Riccardi, O Ciferri.   

Abstract

The mmr gene, cloned from Mycobacterium tuberculosis, was shown to confer to Mycobacterium smegmatis resistance to tetraphenylphosphonium (TPP), erythromycin, ethidium bromide, acriflavine, safranin O, and pyronin Y. The gene appears to code for a protein containing four transmembrane domains. Studies of [3H]TPP intracellular accumulation strongly suggest that the resistance mediated by the Mmr protein involves active extrusion of TPP.

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Year:  1998        PMID： 9811672      PMCID： PMC107688     

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  25 in total

1.  Cloning and characterization of the mvrC gene of Escherichia coli K-12 which confers resistance against methyl viologen toxicity.

Authors:  M Morimyo; E Hongo; H Hama-Inaba; I Machida
Journal:  Nucleic Acids Res       Date:  1992-06-25       Impact factor: 16.971

2.  Rapid mycobacterial plasmid analysis by electroduction between Mycobacterium spp. and Escherichia coli.

Authors:  A Baulard; C Jourdan; A Mercenier; C Locht
Journal:  Nucleic Acids Res       Date:  1992-08-11       Impact factor: 16.971

Review 3.  Genetic systems for mycobacteria.

Authors:  W R Jacobs; G V Kalpana; J D Cirillo; L Pascopella; S B Snapper; R A Udani; W Jones; R G Barletta; B R Bloom
Journal:  Methods Enzymol       Date:  1991       Impact factor: 1.600

4.  Nucleotide sequence of the ethidium efflux gene from Escherichia coli.

Authors:  A S Purewal
Journal:  FEMS Microbiol Lett       Date:  1991-08-01       Impact factor: 2.742

5.  Site-specific recombination promotes linkage between trimethoprim- and sulfonamide resistance genes. Sequence characterization of dhfrV and sulI and a recombination active locus of Tn21.

Authors:  L Sundström; P Rådström; G Swedberg; O Sköld
Journal:  Mol Gen Genet       Date:  1988-08

6.  A staphylococcal multidrug resistance gene product is a member of a new protein family.

Authors:  L Grinius; G Dreguniene; E B Goldberg; C H Liao; S J Projan
Journal:  Plasmid       Date:  1992-03       Impact factor: 3.466

7.  Structure and evolution of a family of genes encoding antiseptic and disinfectant resistance in Staphylococcus aureus.

Authors:  T G Littlejohn; D DiBerardino; L J Messerotti; S J Spiers; R A Skurray
Journal:  Gene       Date:  1991-05-15       Impact factor: 3.688

8.  Emr, an Escherichia coli locus for multidrug resistance.

Authors:  O Lomovskaya; K Lewis
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-01       Impact factor: 11.205

9.  A novel multicopy suppressor of a groEL mutation includes two nested open reading frames transcribed from different promoters.

Authors:  T Greener; D Govezensky; A Zamir
Journal:  EMBO J       Date:  1993-03       Impact factor: 11.598

10.  Molecular cloning and functional analysis of a novel tetracycline resistance determinant, tet(V), from Mycobacterium smegmatis.

Authors:  E De Rossi; M C Blokpoel; R Cantoni; M Branzoni; G Riccardi; D B Young; K A De Smet; O Ciferri
Journal:  Antimicrob Agents Chemother       Date:  1998-08       Impact factor: 5.191
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  29 in total

Review 1.  Macrolide resistance conferred by base substitutions in 23S rRNA.

Authors:  B Vester; S Douthwaite
Journal:  Antimicrob Agents Chemother       Date:  2001-01       Impact factor: 5.191

Review 2.  Molecular properties of bacterial multidrug transporters.

Authors:  M Putman; H W van Veen; W N Konings
Journal:  Microbiol Mol Biol Rev       Date:  2000-12       Impact factor: 11.056

3.  Phage shock proteins B and C prevent lethal cytoplasmic membrane permeability in Yersinia enterocolitica.

Authors:  N Kaye Horstman; Andrew J Darwin
Journal:  Mol Microbiol       Date:  2012-06-12       Impact factor: 3.501

Review 4.  Investigating transport proteins by solid state NMR.

Authors:  Daniel Basting; Ines Lehner; Mark Lorch; Clemens Glaubitz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2006-02-28       Impact factor: 3.000

5.  Efflux pumps of Mycobacterium tuberculosis play a significant role in antituberculosis activity of potential drug candidates.

Authors:  Meenakshi Balganesh; Neela Dinesh; Sreevalli Sharma; Sanjana Kuruppath; Anju V Nair; Umender Sharma
Journal:  Antimicrob Agents Chemother       Date:  2012-02-06       Impact factor: 5.191

Review 6.  A balancing act: efflux/influx in mycobacterial drug resistance.

Authors:  G E Louw; R M Warren; N C Gey van Pittius; C R E McEvoy; P D Van Helden; T C Victor
Journal:  Antimicrob Agents Chemother       Date:  2009-05-18       Impact factor: 5.191

7.  Structure of the EmrE multidrug transporter and its use for inhibitor peptide design.

Authors:  Victor Ovchinnikov; Tracy A Stone; Charles M Deber; Martin Karplus
Journal:  Proc Natl Acad Sci U S A       Date:  2018-08-06       Impact factor: 11.205

8.  Possible Binding of Piperine in Mycobacterium tuberculosis RNA Polymerase and Rifampin Synergism.

Authors:  Letícia Sayuri Murase; João Vítor Perez de Souza; Katiany Rizzieri Caleffi Ferracioli; Rosilene Fressatti Cardoso; Jean Eduardo Meneguello; Flavio Augusto Vicente Seixas; Laíse Adriane Hegeto; Regiane Bertin de Lima Scodro; Vera Lucia Dias Siqueira
Journal:  Antimicrob Agents Chemother       Date:  2019-10-22       Impact factor: 5.191

9.  A small multidrug resistance-like transporter involved in the arabinosylation of arabinogalactan and lipoarabinomannan in mycobacteria.

Authors:  Gérald Larrouy-Maumus; Henrieta Škovierová; Rabeb Dhouib; Shiva Kumar Angala; Sophie Zuberogoitia; Ha Pham; Anne Drumond Villela; Katarina Mikušová; Audrey Noguera; Martine Gilleron; Lucia Valentínová; Jana Korduláková; Patrick J Brennan; Germain Puzo; Jérôme Nigou; Mary Jackson
Journal:  J Biol Chem       Date:  2012-10-04       Impact factor: 5.157

10.  Rv2686c-Rv2687c-Rv2688c, an ABC fluoroquinolone efflux pump in Mycobacterium tuberculosis.

Authors:  Maria Rosalia Pasca; Paola Guglierame; Fabio Arcesi; Marco Bellinzoni; Edda De Rossi; Giovanna Riccardi
Journal:  Antimicrob Agents Chemother       Date:  2004-08       Impact factor: 5.191
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