Literature DB >> 9804943

Non-nociceptive capsaicin-sensitive nerve terminal stimulation allows for an original vasodilatory reflex in the human skin.

B Fromy1, P Abraham, J L Saumet.   

Abstract

A significant increase of cutaneous laser Doppler flowmetry was found before blood flow decreases with increasing pressure during a 5 mmHg min-1 increase of pressure strain on the finger. Pre-treatment with a local anaesthetic or chronically applied capsaicin, resulted in the disappearance of the vasodilatory response. These results suggest an original vasodilatory axon reflex response to non-noxious pressure strain which is initiated by capsaicin-sensitive nerve terminals in the human skin. Copyright 1998 Elsevier Science B.V.

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Year:  1998        PMID： 9804943     DOI： 10.1016/s0006-8993(98)00973-1

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  20 in total

1.  Break excitation alone does not explain the delay and amplitude of anodal current-induced vasodilatation in human skin.

Authors:  S Durand; B Fromy; A Humeau; D Sigaudo-Roussel; J L Saumet; P Abraham
Journal:  J Physiol       Date:  2002-07-15       Impact factor: 5.182

2.  Mechanical compression elicits NO-dependent increases in coronary flow.

Authors:  Dong Sun; An Huang; Gabor Kaley
Journal:  Am J Physiol Heart Circ Physiol       Date:  2004-08-12       Impact factor: 4.733

3.  Altered acetylcholine, bradykinin and cutaneous pressure-induced vasodilation in mice lacking the TREK1 potassium channel: the endothelial link.

Authors:  Ambroise Garry; Bérengère Fromy; Nicolas Blondeau; Daniel Henrion; Frédéric Brau; Pierre Gounon; Nicolas Guy; Catherine Heurteaux; Michel Lazdunski; Jean Louis Saumet
Journal:  EMBO Rep       Date:  2007-03-09       Impact factor: 8.807

4.  Influence of compression pressure from the hand access device on hand microcirculation during hand-assisted laparoscopic surgery.

Authors:  S Manasnayakorn; F Khan; R A Levison; A Cuschieri; G B Hanna
Journal:  Surg Endosc       Date:  2008-10-15       Impact factor: 4.584

5.  Mechanisms of the cutaneous vasodilator response to local external pressure application in rats: involvement of CGRP, neurokinins, prostaglandins and NO.

Authors:  B Fromy; S Merzeau; P Abraham; J L Saumet
Journal:  Br J Pharmacol       Date:  2000-11       Impact factor: 8.739

6.  Measuring niacin-associated skin toxicity (NASTy) stigmata along with symptoms to aid development of niacin mimetics.

Authors:  Richard L Dunbar; Harsh Goel; Sony Tuteja; Wen-Liang Song; Grace Nathanson; Zeeshan Babar; Dusanka Lalic; Joel M Gelfand; Daniel J Rader; Gary L Grove
Journal:  J Lipid Res       Date:  2017-01-23       Impact factor: 5.922

7.  Neuroendocrine pathway involvement in the loss of the cutaneous pressure-induced vasodilatation during acute pain in rats.

Authors:  Bérengère Fromy; Dominique Sigaudo-Roussel; Céline Baron; Yves Roquelaure; Georges Leftheriotis; Jean Louis Saumet
Journal:  J Physiol       Date:  2006-12-07       Impact factor: 5.182

8.  Asic3 is a neuronal mechanosensor for pressure-induced vasodilation that protects against pressure ulcers.

Authors:  Bérengère Fromy; Eric Lingueglia; Dominique Sigaudo-Roussel; Jean Louis Saumet; Michel Lazdunski
Journal:  Nat Med       Date:  2012-07-29       Impact factor: 53.440

9.  Evidence for the involvement of VPAC1 and VPAC2 receptors in pressure-induced vasodilatation in rodents.

Authors:  Lionel Fizanne; Dominique Sigaudo-Roussel; Jean Louis Saumet; Bérengère Fromy
Journal:  J Physiol       Date:  2003-10-24       Impact factor: 5.182

10.  Age-related changes in spontaneous oscillations assessed by wavelet transform of cerebral oxygenation and arterial blood pressure signals.

Authors:  Zengyong Li; Ming Zhang; Qing Xin; Site Luo; Ruofei Cui; Weiei Zhou; Liqian Lu
Journal:  J Cereb Blood Flow Metab       Date:  2013-01-30       Impact factor: 6.200
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