Literature DB >> 979485

Prevention of stress ulcer by somatostatin in rats.

P Mattes, H H Lauterbach, S Raptis.   

Abstract

In animal experiments it was examined, to what extent prophylactic application of Somatostatin is able to prevent the stress-induced ulcer of the rat. 32 male Wistar rats were exposed to a combined immobilisation-hypoxia-stress. Somatostatin was given intraperitoneally as bolus and intravenously as a continuous infusion. The results indicated that Somatostatin lowers significantly the incidence rate of stress-induced gastric ulcers in the rat.

Entities:  

Mesh：

Substances：

Year:  1976        PMID： 979485     DOI： 10.1007/BF01254584

Source DB:  PubMed          Journal:  Langenbecks Arch Chir        ISSN： 0023-8236


  9 in total

1.  Effects of restraint stress on gastric secretion in the rat.

Authors:  R MENGUY
Journal:  Am J Dig Dis       Date:  1960-11

2.  A study of the factors involved in the production of gastric ulcers by the restraint technique.

Authors:  D A BRODIE; H M HANSON
Journal:  Gastroenterology       Date:  1960-03       Impact factor: 22.682

3.  [The role of bile in the development of stress ulcers in the rat].

Authors:  V Schumpelick
Journal:  Dtsch Med Wochenschr       Date:  1975-06-20       Impact factor: 0.628

4.  [Inhibition of pentagastrin-induced gastric-acid secretion by somatostatin in man (author's transl)].

Authors:  R Arnold; W Creutzfeldt
Journal:  Dtsch Med Wochenschr       Date:  1975-05-02       Impact factor: 0.628

5.  The role of mucosal blood flow in the pathogenesis of stress ulcers.

Authors:  W Schellerer
Journal:  Acta Hepatogastroenterol (Stuttg)       Date:  1974-04

6.  Inhibition of gastrin and gastric-acid secretion by growth-hormone release-inhibiting hormone.

Authors:  S R Bloom; C H Mortimer; M O Thorner; G M Besser; R Hall; A Gomez-Pan; V M Roy; R C Russell; D H Coy; A J Kastin; A V Schally
Journal:  Lancet       Date:  1974-11-09       Impact factor: 79.321

7.  Extended somatostatin treatment of a patient with bleeding ulcer.

Authors:  P Mattes; S Raptis; T Heil; H Rasche; R Scheck
Journal:  Horm Metab Res       Date:  1975-11       Impact factor: 2.936

8.  [Effect of somatostatin on betazole-stimulated gastric secretion and carbachol-stimulated pancreatic secretion and gall bladder contraction in man(author's transl)].

Authors:  P G Lankisch; R Arnold; W Creuzfeldt
Journal:  Dtsch Med Wochenschr       Date:  1975-09-05       Impact factor: 0.628

9.  Effects of somatostatin on gastric secretion and gastrin release in man.

Authors:  S Raptis; H C Dollinger; L von Berger; W Schlegel; K E Schröder; E F Pfeiffer
Journal:  Digestion       Date:  1975       Impact factor: 3.216
  9 in total
  4 in total

Review 1.  [The stress ulcer].

Authors:  V Schumpelick; K Horatz; H W Schreiber
Journal:  Langenbecks Arch Chir       Date:  1977-12-14

2.  Gastrointestinal bleeding.

Authors:  A E Read
Journal:  Postgrad Med J       Date:  1984-11       Impact factor: 2.401

3.  The role of the pineal gland in stress.

Authors:  R Miline
Journal:  J Neural Transm       Date:  1980       Impact factor: 3.575

4.  Prevention of stress ulcer by cimetidine and somatostatin in rats.

Authors:  R Vara-Thorbeck; C Garcia-Blanque; A Villen
Journal:  Langenbecks Arch Chir       Date:  1980
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.