Literature DB >> 978184

Effects of interferon on the human clonal cell line, RSa: inhibition of macromolecular synthesis.

A Fuse, T Kuwata.   

Abstract

Multiplication of the human clonal cell line, RSa, is completely inhibited by human leukocyte interferon preparations. Synthesis of DNA and protein is markedly reduced in these cells in proportion to the concentration of interferon applied. Interferon treatment leads to accumulation of cells of an epithelial morphology which do not enter the division cycle. It is suggested that the growth inhibitory effects of interferon on RSa cells may result from these effects.

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Year:  1976        PMID： 978184     DOI： 10.1099/0022-1317-33-1-17

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  9 in total

1.  Effect of cholera toxin on the antiviral and anticellular activities of human leukocyte interferon.

Authors:  A Fuse; T Kuwata
Journal:  Infect Immun       Date:  1979-10       Impact factor: 3.441

2.  Inhibition of cell proliferation by interferons. Relative contributions of changes in protein synthesis and breakdown to growth control of human lymphoblastoid cells.

Authors:  M A McNurlan; M J Clemens
Journal:  Biochem J       Date:  1986-08-01       Impact factor: 3.857

Review 3.  Regulation of cell proliferation and differentiation by interferons.

Authors:  M J Clemens; M A McNurlan
Journal:  Biochem J       Date:  1985-03-01       Impact factor: 3.857

4.  Radioprotective activity of interferon inducers.

Authors:  M Tálas; E Szolgay
Journal:  Arch Virol       Date:  1978       Impact factor: 2.574

5.  Interferon effects on multiplication, cytoplasmic protein and GFAP content, and morphology in human glioma cells.

Authors:  K Korosue; I Takeshita; H Mannoji; M Fukui
Journal:  J Neurooncol       Date:  1983       Impact factor: 4.130

6.  Interferon increases HLA synthesis in melanoma cells: interferon-resistant and -sensitive cell lines.

Authors:  T Y Basham; M F Bourgeade; A A Creasey; T C Merigan
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

7.  Effects of beta interferon on human fibroblasts at different population doubling levels. Proliferation, cell volume, thymidine uptake, and DNA synthesis.

Authors:  B R Jasny; L M Pfeffer; I Tamm
Journal:  J Exp Med       Date:  1984-06-01       Impact factor: 14.307

8.  Interferon effects on microfilament organization, cellular fibronectin distribution, and cell motility in human fibroblasts.

Authors:  L M Pfeffer; E Wang; I Tamm
Journal:  J Cell Biol       Date:  1980-04       Impact factor: 10.539

9.  Dipyridamole combined with tumor necrosis factor-alpha enhances inhibition of proliferation in human tumor cell lines.

Authors:  N Suzuki; S Sekiya; I Sugano; T Kojima; H Yamamori; Y Takakubo
Journal:  Jpn J Cancer Res       Date:  1995-08
  9 in total

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