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Literature DB >> 9770440

A role for the beta-amyloid precursor protein in memory?

S S Sisodia¹, M Gallagher.

Abstract

Mesh：

Substances：

Year: 1998 PMID： 9770440 PMCID： PMC33903 DOI： 10.1073/pnas.95.21.12074

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

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45 in total

1. Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing.

Authors: S S Sisodia; E H Koo; K Beyreuther; A Unterbeck; D L Price
Journal: Science Date: 1990-04-27 Impact factor: 47.728

Review 2. Amyloidogenesis in Alzheimer's disease: some possible therapeutic opportunities.

Authors: S Gandy; P Greengard
Journal: Trends Pharmacol Sci Date: 1992-03 Impact factor: 14.819

3. Cleavage of amyloid beta peptide during constitutive processing of its precursor.

Authors: F S Esch; P S Keim; E C Beattie; R W Blacher; A R Culwell; T Oltersdorf; D McClure; P J Ward
Journal: Science Date: 1990-06-01 Impact factor: 47.728

4. The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth.

Authors: E A Milward; R Papadopoulos; S J Fuller; R D Moir; D Small; K Beyreuther; C L Masters
Journal: Neuron Date: 1992-07 Impact factor: 17.173

5. Beta-amyloid precursor protein cleavage by a membrane-bound protease.

Authors: S S Sisodia
Journal: Proc Natl Acad Sci U S A Date: 1992-07-01 Impact factor: 11.205

6. Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

Authors: C Haass; E H Koo; A Mellon; A Y Hung; D J Selkoe
Journal: Nature Date: 1992-06-11 Impact factor: 49.962

7. Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor.

Authors: J D Buxbaum; M Oishi; H I Chen; R Pinkas-Kramarski; E A Jaffe; S E Gandy; P Greengard
Journal: Proc Natl Acad Sci U S A Date: 1992-11-01 Impact factor: 11.205

8. Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage.

Authors: A Y Hung; E H Koo; C Haass; D J Selkoe
Journal: Proc Natl Acad Sci U S A Date: 1992-10-15 Impact factor: 11.205

9. Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor.

Authors: W Wasco; K Bupp; M Magendantz; J F Gusella; R E Tanzi; F Solomon
Journal: Proc Natl Acad Sci U S A Date: 1992-11-15 Impact factor: 11.205

A role for the beta-amyloid precursor protein in memory?

1. Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing.

Review 2. Amyloidogenesis in Alzheimer's disease: some possible therapeutic opportunities.

3. Cleavage of amyloid beta peptide during constitutive processing of its precursor.

4. The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth.

5. Beta-amyloid precursor protein cleavage by a membrane-bound protease.

6. Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

7. Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor.

8. Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage.

9. Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor.

10. Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors.

1. Solution studies and structural model of the extracellular domain of the human amyloid precursor protein.

2. G protein-coupled receptors as disease targets: emerging paradigms.

Review 3. Role of the immune system in the pathogenesis, prevention and treatment of Alzheimer's disease.

4. Lipid rafts and Alzheimer's disease: protein-lipid interactions and perturbation of signaling.

5. What does complement do in Alzheimer's disease? Old molecules with new insights.

Review 6. Alzheimer Disease: Crosstalk between the Canonical Wnt/Beta-Catenin Pathway and PPARs Alpha and Gamma.