BACKGROUND: There is evidence to suggest a masculinizing effect on female intrauterine development in unlike-sexed twins. The purpose of the present report was to examine the possible effects of male presence on fetal growth in females by comparing mean birthweights in members from dizygotic unlike-sexed (DZU) pairs with those from dizygotic like-sexed (DZL) pairs. METHODS: The sample consisted of 1087 DZU and 1089 DZL twin pairs from the New Norwegian Twin Panel, which was established by identifying all twin births from 1967 to 1974 through the population-based Medical Birth Registry. RESULTS: The mean birthweight of females from DZU pairs was 2684+/-15 g (+/-SEM), as opposed to 2647+/-19 g in females from DZL pairs (P = 0.06). For males, the mean birthweight was 2812+/-16 g in DZU pairs and 2805+/-20 g in DZL pairs (P= 0.78). CONCLUSION: We found a tendency for the birthweight in females to be influenced by the presence of a male co-twin. This observation may have a biological significance and should lead to a close follow-up of DZU and DZL females with respect to hormone-sensitive disorders and reproductive ability.
BACKGROUND: There is evidence to suggest a masculinizing effect on female intrauterine development in unlike-sexed twins. The purpose of the present report was to examine the possible effects of male presence on fetal growth in females by comparing mean birthweights in members from dizygotic unlike-sexed (DZU) pairs with those from dizygotic like-sexed (DZL) pairs. METHODS: The sample consisted of 1087 DZU and 1089 DZL twin pairs from the New Norwegian Twin Panel, which was established by identifying all twin births from 1967 to 1974 through the population-based Medical Birth Registry. RESULTS: The mean birthweight of females from DZU pairs was 2684+/-15 g (+/-SEM), as opposed to 2647+/-19 g in females from DZL pairs (P = 0.06). For males, the mean birthweight was 2812+/-16 g in DZU pairs and 2805+/-20 g in DZL pairs (P= 0.78). CONCLUSION: We found a tendency for the birthweight in females to be influenced by the presence of a male co-twin. This observation may have a biological significance and should lead to a close follow-up of DZU and DZL females with respect to hormone-sensitive disorders and reproductive ability.
Authors: Laura N Vandenberg; Theo Colborn; Tyrone B Hayes; Jerrold J Heindel; David R Jacobs; Duk-Hee Lee; Toshi Shioda; Ana M Soto; Frederick S vom Saal; Wade V Welshons; R Thomas Zoeller; John Peterson Myers Journal: Endocr Rev Date: 2012-03-14 Impact factor: 19.871
Authors: Leonie H Bogl; Aline Jelenkovic; Eero Vuoksimaa; Linda Ahrenfeldt; Kirsi H Pietiläinen; Maria A Stazi; Corrado Fagnani; Cristina D'Ippolito; Yoon-Mi Hur; Hoe-Uk Jeong; Judy L Silberg; Lindon J Eaves; Hermine H Maes; Gombojav Bayasgalan; Danshiitsoodol Narandalai; Tessa L Cutler; Christian Kandler; Kerry L Jang; Kaare Christensen; Axel Skytthe; Kirsten O Kyvik; Wendy Cozen; Amie E Hwang; Thomas M Mack; Catherine A Derom; Robert F Vlietinck; Tracy L Nelson; Keith E Whitfield; Robin P Corley; Brooke M Huibregtse; Tom A McAdams; Thalia C Eley; Alice M Gregory; Robert F Krueger; Matt McGue; Shandell Pahlen; Gonneke Willemsen; Meike Bartels; Toos C E M van Beijsterveldt; Zengchang Pang; Qihua Tan; Dongfeng Zhang; Nicholas G Martin; Sarah E Medland; Grant W Montgomery; Jacob V B Hjelmborg; Esther Rebato; Gary E Swan; Ruth Krasnow; Andreas Busjahn; Paul Lichtenstein; Sevgi Y Öncel; Fazil Aliev; Laura A Baker; Catherine Tuvblad; Sisira H Siribaddana; Matthew Hotopf; Athula Sumathipala; Fruhling Rijsdijk; Patrik K E Magnusson; Nancy L Pedersen; Anna K Dahl Aslan; Juan R Ordoñana; Juan F Sánchez-Romera; Lucia Colodro-Conde; Glen E Duncan; Dedra Buchwald; Adam D Tarnoki; David L Tarnoki; Yoshie Yokoyama; John L Hopper; Ruth J F Loos; Dorret I Boomsma; Thorkild I A Sørensen; Karri Silventoinen; Jaakko Kaprio Journal: Biol Sex Differ Date: 2017-04-27 Impact factor: 5.027
Authors: Aline Jelenkovic; Reijo Sund; Yoshie Yokoyama; Yoon-Mi Hur; Vilhelmina Ullemar; Catarina Almqvist; Patrik Ke Magnusson; Gonneke Willemsen; Meike Bartels; Catharina Em van Beijsterveldt; Leonie H Bogl; Kirsi H Pietiläinen; Eero Vuoksimaa; Fuling Ji; Feng Ning; Zengchang Pang; Tracy L Nelson; Keith E Whitfield; Esther Rebato; Clare H Llewellyn; Abigail Fisher; Gombojav Bayasgalan; Danshiitsoodol Narandalai; Morten Bjerregaard-Andersen; Henning Beck-Nielsen; Morten Sodemann; Adam D Tarnoki; David L Tarnoki; Syuichi Ooki; Maria A Stazi; Corrado Fagnani; Sonia Brescianini; Lise Dubois; Michel Boivin; Mara Brendgen; Ginette Dionne; Frank Vitaro; Tessa L Cutler; John L Hopper; Robert F Krueger; Matt McGue; Shandell Pahlen; Jeffrey M Craig; Richard Saffery; Claire Ma Haworth; Robert Plomin; Ariel Knafo-Noam; David Mankuta; Lior Abramson; S Alexandra Burt; Kelly L Klump; Robert F Vlietinck; Catherine A Derom; Ruth Jf Loos; Dorret I Boomsma; Thorkild I A Sørensen; Jaakko Kaprio; Karri Silventoinen Journal: Sci Rep Date: 2018-04-19 Impact factor: 4.379