Literature DB >> 972147

The NH2- and COOH-terminal amino acid sequence of nuclear protein A24.

M O Olson, I L Goldknopf, K A Guetzow, G T James, T C Hawkins, C J Mays-Rothberg, H Busch.   

Abstract

The NH2- and COOH-terminal sequence of nuclear portein A24 has been determined by automatic Edman degradation and carboxypeptidase A and B digestion. Protein A24 is of interest because it is composed in part of histone 2A (Goldknofp, I.L., and Busch, H., (1975) Biochem, Biophys. Res. Commun. 65, 951-960). The sequence of the first 37 NH2-terminal residues is: Met-Gln-Ile-Phe-Val-Lys-Thr-Leu-Thr-Gly-Lys-Thr-Ile-Thr-Leu-Glu-Val-Glu-Pro-Ser-Asp-Thr-Ile-Glu-Asn-Val-Lys-Ala-Lys-Ile-Gln-Asp-Lys-Glu-Gly-Ile-Pro- This sequence is not homologous to any known histone sequence. It contains regions of internal homology (italics). The COOH-terminal amino acid sequence is the same as that of histone 2A, naely: -His-His-Lys-Ala-Lys-Gly-Lys-COOH.

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Year:  1976        PMID： 972147

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  12 in total

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Authors:  I L Goldknopf; M F French; R Musso; H Busch
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

3.  The effect of cycloheximide on nuclear uH2A content.

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4.  Ubiquitin - protein conjugates.

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Journal:  Mol Cell Biochem       Date:  1981-11-13       Impact factor: 3.396

5.  High-resolution fractionation of nucleosomes: minor particles, "whiskers," and separation of mononucleosomes containing and lacking A24 semihistone.

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7.  Antigenic differences in nuclear proteins of normal liver and hepatoma. Identification of a nuclear protein present in hepatocytes but absent in hepatoma cells.

Authors:  E Ruoslahti; E Engvall; H Jalanko; D E Commings
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Review 8.  Chemical strategies to understand the language of ubiquitin signaling.

Authors:  Caroline E Weller; Meagan E Pilkerton; Champak Chatterjee
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9.  Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24.

Authors:  I L Goldknopf; H Busch
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

10.  Genome-wide uH2A localization analysis highlights Bmi1-dependent deposition of the mark at repressed genes.

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