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Literature DB >> 6096161

The effect of cycloheximide on nuclear uH2A content.

Abstract

The effect of intraperitonal cycloheximide administration on acid-soluble rat liver chromatin proteins has been investigated by electrophoresis in acetic acid-urea polyacrylamide gels. A nonhistone protein, which migrates between oxidized histone H3 and histone H1 has been found to be increased in amount following cycloheximide treatment. This protein seems to be identical with semihistone protein H24 (uH2A). A possible relationship of uH2A to the inhibition of rRNA synthesis is discussed.

Entities: Chemical Gene Species

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Year: 1984 PMID： 6096161 DOI： 10.1007/bf01951910

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

24 in total

1. Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells.

Authors: G Goldstein; M Scheid; U Hammerling; D H Schlesinger; H D Niall; E A Boyse
Journal: Proc Natl Acad Sci U S A Date: 1975-01 Impact factor: 11.205

2. Enhanced transcription by RNA polymerases II and III after inhibition of protein synthesis.

Authors: T J Lindell; J J Duffy
Journal: J Biol Chem Date: 1979-03-10 Impact factor: 5.157

3. High salt effect on RNA synthesis in Krebs ascites tumor cells.

Authors: S Gökçe; B Kan; B Kirdar; E Bermek
Journal: Experientia Date: 1982-06-15

4. Increases in protein A24 following treatment of Ehrlich ascites tumor cells with 1-methyl-1-nitrosourea and 1,3-bis(2-chloroethyl)-1-nitrosourea.

Authors: J M Dornish; I Smith-Kielland
Journal: FEBS Lett Date: 1981-12-21 Impact factor: 4.124

5. The complete amino acid sequence of ubiquitin, an adenylate cyclase stimulating polypeptide probably universal in living cells.

Authors: D H Schlesinger; G Goldstein; H D Niall
Journal: Biochemistry Date: 1975-05-20 Impact factor: 3.162

6. Disappearance of a structural chromatin protein A24 in mitosis: implications for molecular basis of chromatin condensation.

Authors: S I Matsui; B K Seon; A A Sandberg
Journal: Proc Natl Acad Sci U S A Date: 1979-12 Impact factor: 11.205

The effect of cycloheximide on nuclear uH2A content.

1. Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells.

2. Enhanced transcription by RNA polymerases II and III after inhibition of protein synthesis.

3. High salt effect on RNA synthesis in Krebs ascites tumor cells.

4. Increases in protein A24 following treatment of Ehrlich ascites tumor cells with 1-methyl-1-nitrosourea and 1,3-bis(2-chloroethyl)-1-nitrosourea.

5. The complete amino acid sequence of ubiquitin, an adenylate cyclase stimulating polypeptide probably universal in living cells.

6. Disappearance of a structural chromatin protein A24 in mitosis: implications for molecular basis of chromatin condensation.

7. Chromatin conjugate protein A24 is cleaved and ubiquitin is lost during chicken erythropoiesis.

8. Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24.

9. Activation of the heat-stable polypeptide of the ATP-dependent proteolytic system.

10. The regulation of RNA synthesis and processing in the nucleolus during inhibition of protein synthesis.

1. Binding of protein uH2A and histone H2A to DNA.