Literature DB >> 971757

RNA synthesis in alpha-amanitin-poisoned rats: prevention of recovery by inhibition of protein synthesis.

M Derenzini, F Novello.   

Abstract

The treatment with cycloheximide of rats previously poisoned with alpha-amanitin hinders the recovery of RNA synthesis observed in the liver of rats treated with alpha-amanitin alone. The recovery of RNA synthesis can be ascribed to the capability of poisoned rats to synthesize new RNA-polymerase II.

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Year:  1976        PMID： 971757     DOI： 10.1007/BF01927616

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  12 in total

1.  Production of antibodies to amanitins as the basis for their radioimmunoassay.

Authors:  L Fiume; C Busi; G Campadelli-Fiume; C Franceschi
Journal:  Experientia       Date:  1975-10-15

2.  Inhibition of ribonucleic acid and of protein synthesis in the organs of rats and mice poisoned with alpha-amanitin.

Authors:  L Montanaro; F Novello; F Stirpe
Journal:  Biochim Biophys Acta       Date:  1973-08-24

3.  Effects of -amanitin on mouse and rat liver cell nuclei.

Authors:  V Marinozzi; L Fiume
Journal:  Exp Cell Res       Date:  1971-08       Impact factor: 3.905

Review 4.  Recent developments in the measurement of nucleic acids in biological materials. A supplementary review.

Authors:  H N Munro; A Fleck
Journal:  Analyst       Date:  1966-02       Impact factor: 4.616

5.  The biochemical pathology of inhibition of protein synthesis in vivo. The effects of cycloheximide on hepatic parenchymal cell ultrastructure.

Authors:  R S Verbin; P J Goldblatt; E Farber
Journal:  Lab Invest       Date:  1969-06       Impact factor: 5.662

6.  The effects of amanitin poisoning on mouse kidney.

Authors:  L Fiume; V Marinozzi; F Nardi
Journal:  Br J Exp Pathol       Date:  1969-06

7.  [Ultrastructural lesions produced in hepatic parenchymal cells by phalloidin and alpha-amanitin].

Authors:  L Fiume; R Laschi
Journal:  Sperimentale       Date:  1965 Sep-Oct

8.  Effect of cycloheximide on protein biosynthesis in rat liver.

Authors:  A Korner
Journal:  Biochem J       Date:  1966-12       Impact factor: 3.857

9.  Studies on the pathogenesis of liver necrosis by alpha-amanitin. Effect of alpha-amanitin on ribonucleic acid synthesis and on ribonucleic acid polymerase in mouse liver nuclei.

Authors:  F Stirpe; L Fiume
Journal:  Biochem J       Date:  1967-11       Impact factor: 3.857

10.  CYCLOHEXIMIDE: ASPECTS OF INHIBITION OF PROTEIN SYNTHESIS IN MAMMALIAN CELLS.

Authors:  H L ENNIS; M LUBIN
Journal:  Science       Date:  1964-12-11       Impact factor: 47.728
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