Literature DB >> 1204754

Production of antibodies to amanitins as the basis for their radioimmunoassay.

L Fiume, C Busi, G Campadelli-Fiume, C Franceschi.   

Abstract

The production of antibodies against amanitins is described. By means of these antibodies, a radioimmunoassay was developed which allows detection of as little as 0.5 ng of amanitins in 1 ml of serum. By this method, the clearance of alpha-amanitin from the blood of poisoned mice was measured.

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Year:  1975        PMID： 1204754     DOI： 10.1007/bf02326810

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  Amantis. Chemistry and action.

Authors:  L Fiume; T Wielannd
Journal:  FEBS Lett       Date:  1970-05-11       Impact factor: 4.124

2.  [Effects of alpha amanitin, the poison of amanita phalloides].

Authors:  O WIELAND; H E FISCHER; M REITER
Journal:  Naunyn Schmiedebergs Arch Exp Pathol Pharmakol       Date:  1952

3.  Selective killing of macrophages by amanitin-albumin conjugates.

Authors:  G Barbanti-Brodano; L Fiume
Journal:  Nat New Biol       Date:  1973-06-27

4.  Pathogenesis of liver necrosis produced by amanitin-albumin conjugates.

Authors:  M Derenzini; L Fiume; V Marinozzi; A Mattioli; L Montanaro; S Sperti
Journal:  Lab Invest       Date:  1973-08       Impact factor: 5.662

5.  Toxicity of and inhibition of RNA polymerase by alpha-amanitin bound to macromolecules by an Azo linkage.

Authors:  H Faulstich; H Trischmann
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1973 Oct-Nov

Review 6.  Poisonous principles of mushrooms of the genus Amanita. Four-carbon amines acting on the central nervous system and cell-destroying cyclic peptides are produced.

Authors:  T Wieland
Journal:  Science       Date:  1968-03-01       Impact factor: 47.728

7.  [Hemodialysis in Amanita phalloides poisoning. Serum levels and excretion of amanitine].

Authors:  H Faulstich; U Fauser
Journal:  Dtsch Med Wochenschr       Date:  1973-11-23       Impact factor: 0.628

8.  Increased toxicity of beta-amanitin when bound to a protein.

Authors:  C Cessi; L Fiume
Journal:  Toxicon       Date:  1969-05       Impact factor: 3.033

9.  Lesions in the cells of proximal convoluted tubules in rat kidney induced by amanitin-albumin conjugate.

Authors:  E Bonetti; M Derenzini; L Fiume
Journal:  Virchows Arch B Cell Pathol       Date:  1974
  9 in total
  6 in total

1.  RNA synthesis in alpha-amanitin-poisoned rats: prevention of recovery by inhibition of protein synthesis.

Authors:  M Derenzini; F Novello
Journal:  Experientia       Date:  1976-09-15

2.  Increased penetration of amanitine into hepatocytes when conjugated with albumin.

Authors:  E Bonetti; M Derenzini; L Fiume
Journal:  Arch Toxicol       Date:  1976-01-30       Impact factor: 5.153

Review 3.  New aspects of amanita poisoning.

Authors:  H Faulstich
Journal:  Klin Wochenschr       Date:  1979-11-02

4.  A study on the pharmacokinetics in mouse of adenine-9-beta-D-arabinofuranoside 5-monophosphate conjugated with lactosaminated albumin.

Authors:  L Fiume; B Bassi; C Busi; A Mattioli; T Wieland
Journal:  Experientia       Date:  1985-10-15

5.  [The early removal of amatoxins in the treatment of amanita phalloides poisoning (author's transl)].

Authors:  M Langer; S Vesconi; G Iapichino; D Costantino; D Radrizzani
Journal:  Klin Wochenschr       Date:  1980-02-01

6.  A New Conjugation Method Used for the Development of an Immunoassay for the Detection of Amanitin, a Deadly Mushroom Toxin.

Authors:  Candace S Bever; Bogdan Barnych; Robert Hnasko; Luisa W Cheng; Larry H Stanker
Journal:  Toxins (Basel)       Date:  2018-06-28       Impact factor: 4.546
  6 in total

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