| Literature DB >> 9708553 |
J Vaughan1, A Durr, J Tassin, B Bereznai, T Gasser, V Bonifati, G De Michele, E Fabrizio, G Volpe, O Bandmann, W G Johnson, L I Golbe, M Breteler, G Meco, Y Agid, A Brice, C D Marsden, N W Wood.
Abstract
We report the results of a screen of 230 European familial index cases of Parkinson's disease for the recently described Ala53Thr mutation in the alpha-synuclein gene in an autosomal dominant Parkinson's disease kindred. No mutations were found from this broad white population, and we therefore conclude that although of great interest, this mutation is a very rare cause of familial Parkinson's disease.Entities:
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Year: 1998 PMID： 9708553 DOI： 10.1002/ana.410440221
Source DB: PubMed Journal: Ann Neurol ISSN： 0364-5134 Impact factor: 10.422