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Literature DB >> 11724911

The aetiology of idiopathic Parkinson's disease.

D B Ramsden¹, R B Parsons, S L Ho, R H Waring.

Abstract

Agents potentially involved in the aetiology of idiopathic Parkinson's disease are discussed. These include factors regulating dopaminergic neurogenesis (Nurr 1, Ptx-3, and Lmx1b) and related proteins, together with genes involved in familial Parkinson's disease (alpha synuclein, parkin, and ubiquitin carboxy terminal hydroxylase L1), and endogenous and environmental agents.

Entities: Disease Gene

Mesh：

Substances：

Year: 2001 PMID： 11724911 PMCID： PMC1187126

Source DB: PubMed Journal: Mol Pathol ISSN： 1366-8714

176 in total

1. Fate of mesencephalic AHD2-expressing dopamine progenitor cells in NURR1 mutant mice.

Authors: A Wallén; R H Zetterström; L Solomin; M Arvidsson; L Olson; T Perlmann
Journal: Exp Cell Res Date: 1999-12-15 Impact factor: 3.905

2. Activity of the Nurr1 carboxyl-terminal domain depends on cell type and integrity of the activation function 2.

Authors: D S Castro; M Arvidsson; M Bondesson Bolin; T Perlmann
Journal: J Biol Chem Date: 1999-12-24 Impact factor: 5.157

3. Apolipoprotein E polymorphisms and Parkinson's disease.

Authors: R L Oliveri; G Nicoletti; R Cittadella; I Manna; D Branca; M Zappia; A Gambardella; M Caracciolo; A Quattrone
Journal: Neurosci Lett Date: 1999-12-24 Impact factor: 3.046

4. The dopamine D2 receptor gene is a susceptibility locus for Parkinson's disease.

Authors: R L Oliveri; G Annesi; M Zappia; D Civitelli; E V De Marco; A A Pasqua; F Annesi; P Spadafora; A Gambardella; G Nicoletti; D Branca; M Caracciolo; U Aguglia; A Quattrone
Journal: Mov Disord Date: 2000-01 Impact factor: 10.338

5. Detailed genotyping demonstrates association between the slow acetylator genotype for N-acetyltransferase 2 (NAT2) and familial Parkinson's disease.

Authors: O Bandmann; J R Vaughan; P Holmans; C D Marsden; N W Wood
Journal: Mov Disord Date: 2000-01 Impact factor: 10.338

6. Environmental, medical, and family history risk factors for Parkinson's disease: a New England-based case control study.

Authors: C A Taylor; M H Saint-Hilaire; L A Cupples; C A Thomas; A E Burchard; R G Feldman; R H Myers
Journal: Am J Med Genet Date: 1999-12-15

7. Early induction of the orphan nuclear receptor NOR-1 during cell death of the human breast cancer cell line MCF-7.

Authors: T Ohkubo; N Ohkura; K Maruyama; K Sasaki; K Nagasaki; H Hanzawa; T Tsukada; K Yamaguchi
Journal: Mol Cell Endocrinol Date: 2000-04-25 Impact factor: 4.102

8. Deletion of a branch-point consensus sequence in the LMX1B gene causes exon skipping in a family with nail patella syndrome.

Authors: J D Hamlington; M V Clough; J A Dunston; I McIntosh
Journal: Eur J Hum Genet Date: 2000-04 Impact factor: 4.246

9. Increased beta-carboline 9N-methyltransferase activity in the frontal cortex in Parkinson's disease.

Authors: D A Gearhart; M A Collins; J M Lee; E J Neafsey
Journal: Neurobiol Dis Date: 2000-06 Impact factor: 5.996

10. Familial aggregation of Parkinson's disease in a Finnish population.

Authors: J M Autere; J S Moilanen; V V Myllylä; K Majamaa
Journal: J Neurol Neurosurg Psychiatry Date: 2000-07 Impact factor: 10.154

13 in total

Review 1. Etiology of Parkinson's disease: Genetics and environment revisited.

Authors: Kathy Steece-Collier; Eleonora Maries; Jeffrey H Kordower
Journal: Proc Natl Acad Sci U S A Date: 2002-10-21 Impact factor: 11.205

Review 2. Rodent models and contemporary molecular techniques: notable feats yet incomplete explanations of Parkinson's disease pathogenesis.

Authors: Sharawan Yadav; Anubhuti Dixit; Sonal Agrawal; Ashish Singh; Garima Srivastava; Anand Kumar Singh; Pramod Kumar Srivastava; Om Prakash; Mahendra Pratap Singh
Journal: Mol Neurobiol Date: 2012-06-27 Impact factor: 5.590

3. Apoptotic natural cell death in developing primate dopamine midbrain neurons occurs during a restricted period in the second trimester of gestation.

Authors: Bret A Morrow; Robert H Roth; D Eugene Redmond; John R Sladek; John D Elsworth
Journal: Exp Neurol Date: 2007-01-19 Impact factor: 5.330

4. Basic fibroblast growth factor protects against rotenone-induced dopaminergic cell death through activation of extracellular signal-regulated kinases 1/2 and phosphatidylinositol-3 kinase pathways.

Authors: Shih-Ling Hsuan; Heather M Klintworth; Zhengui Xia
Journal: J Neurosci Date: 2006-04-26 Impact factor: 6.167

Review 5. Pathological proteins in Parkinson's disease: focus on the proteasome.

Authors: Heather Snyder; Benjamin Wolozin
Journal: J Mol Neurosci Date: 2004 Impact factor: 3.444

6. In silico QTL mapping of basal liver iron levels in inbred mouse strains.

Authors: Stela McLachlan; Seung-Min Lee; Teresa M Steele; Paula L Hawthorne; Matthew A Zapala; Eleazar Eskin; Nicholas J Schork; Gregory J Anderson; Chris D Vulpe
Journal: Physiol Genomics Date: 2010-11-09 Impact factor: 3.107

Review 7. The genetics of Parkinson's disease.

Authors: Kah Leong Lim; Valina L Dawson; Ted M Dawson
Journal: Curr Neurol Neurosci Rep Date: 2002-09 Impact factor: 5.081

8. JNK inhibition of VMAT2 contributes to rotenone-induced oxidative stress and dopamine neuron death.

Authors: Won-Seok Choi; Hyung-Wook Kim; Zhengui Xia
Journal: Toxicology Date: 2014-12-09 Impact factor: 4.221

9. Protein reactivity of 3,4-dihydroxyphenylacetaldehyde, a toxic dopamine metabolite, is dependent on both the aldehyde and the catechol.

Authors: Jennifer N Rees; Virginia R Florang; Laurie L Eckert; Jonathan A Doorn
Journal: Chem Res Toxicol Date: 2009-07 Impact factor: 3.739

Review 10. Model fusion, the next phase in developing animal models for Parkinson's disease.

Authors: Amy B Manning-Bog; J William Langston
Journal: Neurotox Res Date: 2007-04 Impact factor: 3.911