Literature DB >> 96815

Separation of oestrone UDP-glucuronyltransferase and p-nitrophenol UDP-glucuronyltransferase activities.

R H Tukey, R E Billings, T R Tephly.   

Abstract

Rabbit liver UDP-glucuronyltransferase activity was resolved into two separate fractions on DEAE-cellulose, one containing most of the transferase activity toward oestrone and the other most of the activity toward p-nitrophenol. These two activities were completely separated by rechromatography of each fraction on a second DEAE-cellulose column.

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Year:  1978        PMID： 96815      PMCID： PMC1184011          DOI： 10.1042/bj1710659

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  27 in total

1.  The solubilization and partial purification of a glucuronyl transferase from rabbit liver microsomes.

Authors:  K J ISSELBACHER; M F CHRABAS; R C QUINN
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2.  The synthesis of bilirubin glucuronide in animal and human liver.

Authors:  G H LATHE; M WALKER
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3.  Uridine diphosphate glucuronic acid as glucuronyl donor in the synthesis of ester, aliphatic and steroid glucuronides.

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Journal:  Biochem J       Date:  1956-12       Impact factor: 3.857

4.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

5.  Acid precipitation of protein in the presence of triton X-100 and deoxycholate.

Authors:  K C Retz; W J Steele
Journal:  Anal Biochem       Date:  1977-05-01       Impact factor: 3.365

6.  Purification of UDP-glucuronyltransferase from untreated rat liver.

Authors:  B Burchell
Journal:  FEBS Lett       Date:  1977       Impact factor: 4.124

7.  Studies on the properties of an enzyme forming the glucuronide of pregnanediol and the pattern of development of steroid glucuronyltransferases in rat liver.

Authors:  M Fuchs; G S Rao; M L Rao; H Breuer
Journal:  J Steroid Biochem       Date:  1977-03       Impact factor: 4.292

8.  Morphine metabolism. V. Isolation of separate glucuronyltransferase activities for morphine and p-nitrophenol from rabbit liver microsomes.

Authors:  E D Villar; E Sanchez; T R Tephly
Journal:  Drug Metab Dispos       Date:  1977 May-Jun       Impact factor: 3.922

9.  Ethereal and N-linked glucuronide formation by normal and Gunn rats in vitro and in vivo.

Authors:  I M ARIAS
Journal:  Biochem Biophys Res Commun       Date:  1961-11-01       Impact factor: 3.575

10.  Purification and properties of microsomal UDP-glucuronosyltransferase from rat liver.

Authors:  J P Gorski; C B Kasper
Journal:  J Biol Chem       Date:  1977-02-25       Impact factor: 5.157
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  10 in total

1.  Influence of growth hormone on the hepatic mixed function oxidase and transferase systems of rainbow trout.

Authors:  J P Cravedi; A Paris; E Perdu-Durand; P Prunet
Journal:  Fish Physiol Biochem       Date:  1995-08       Impact factor: 2.794

2.  The separation and purification of rat liver UDP-glucuronyltransferase activities towards testosterone and oestrone.

Authors:  P J Weatherill; B Burchell
Journal:  Biochem J       Date:  1980-08-01       Impact factor: 3.857

3.  Immunochemical comparison of UDP-glucuronyltransferase from Gunn- and Wistar-rat livers.

Authors:  P J Weatherill; S M Kennedy; B Burchell
Journal:  Biochem J       Date:  1980-10-01       Impact factor: 3.857

4.  Diabetes in female rats; changes in liver microsomal aminopyrine N-demethylase and UDP-glucuronyl transferase activities.

Authors:  E Del Villar; P Vega; C Gaule; E Sanchez
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1990 Oct-Dec       Impact factor: 2.441

5.  Strain differences in rat liver (UDP-glucuronyltransferase activity towards androsterone.

Authors:  M Matsui; F Nagai; S Aoyagi
Journal:  Biochem J       Date:  1979-06-01       Impact factor: 3.857

6.  Phospholipid-dependence of oestrone UDP-glucuronyltransferase and p-nitrophenol UDP-glucuronyltransferase.

Authors:  R H Tukey; R E Billings; A P Autor; T R Tephly
Journal:  Biochem J       Date:  1979-04-01       Impact factor: 3.857

7.  Isolation of multiple normal and functionally defective forms of uridine diphosphate-glucuronosyltransferase from inbred Gunn rats.

Authors:  N Roy Chowdhury; F Gross; A D Moscioni; M Kram; I M Arias; J Roy Chowdhury
Journal:  J Clin Invest       Date:  1987-02       Impact factor: 14.808

8.  Strain differences in purified rat hepatic 3 alpha-hydroxysteroid UDP-glucuronosyltransferase.

Authors:  M D Green; C N Falany; R B Kirkpatrick; T R Tephly
Journal:  Biochem J       Date:  1985-09-01       Impact factor: 3.857

9.  Human UGT1A8 and UGT1A10 mRNA are expressed in primary human hepatocytes.

Authors:  Xin Li; Stacie Bratton; Anna Radominska-Pandya
Journal:  Drug Metab Pharmacokinet       Date:  2007-06       Impact factor: 3.614

10.  Isothiocyanates induce UGT1A1 in humanized UGT1 mice in a CAR dependent fashion that is highly dependent upon oxidative stress.

Authors:  Emiko Yoda; Miles Paszek; Camille Konopnicki; Ryoichi Fujiwara; Shujuan Chen; Robert H Tukey
Journal:  Sci Rep       Date:  2017-04-19       Impact factor: 4.379
  10 in total

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