PURPOSE: Our goal was to evaluate CT angiography (CTA) in diagnosing renal artery stenosis (RAS). METHOD: Thirty-seven patients underwent digital subtraction angiography (DSA) and CTA. Visual interpretation and stenosis measurements were made from maximum intensity projection (MIP) and multiplanar reformation (MPR) laser film prints of 78 renal arteries. RESULTS: Visual reading of MIP films showed good diagnostic performance by receiver operating characteristic curve analysis, with 100% sensitivity in the assessment of > or = 50% RAS but only 42-54% specificity (overall accuracy 60-75%). The false-positive rate decreased when MIP and MPR films were read together, but the excess of false negatives among the calcified lesions disabled this diagnostic algorithm. Combining visual interpretation of MIP films with quantitative measurements yielded the best diagnostic performance: 92% sensitivity, 80% specificity, and 84% overall accuracy. Renal cortical enhancement measurements (26 patients) had 81% overall accuracy. CONCLUSION: The overall accuracy of CTA with MIP film reading can be enhanced by quantitative measurement of stenosis or reviewing MPRs.
PURPOSE: Our goal was to evaluate CT angiography (CTA) in diagnosing renal artery stenosis (RAS). METHOD: Thirty-seven patients underwent digital subtraction angiography (DSA) and CTA. Visual interpretation and stenosis measurements were made from maximum intensity projection (MIP) and multiplanar reformation (MPR) laser film prints of 78 renal arteries. RESULTS: Visual reading of MIP films showed good diagnostic performance by receiver operating characteristic curve analysis, with 100% sensitivity in the assessment of > or = 50% RAS but only 42-54% specificity (overall accuracy 60-75%). The false-positive rate decreased when MIP and MPR films were read together, but the excess of false negatives among the calcified lesions disabled this diagnostic algorithm. Combining visual interpretation of MIP films with quantitative measurements yielded the best diagnostic performance: 92% sensitivity, 80% specificity, and 84% overall accuracy. Renal cortical enhancement measurements (26 patients) had 81% overall accuracy. CONCLUSION: The overall accuracy of CTA with MIP film reading can be enhanced by quantitative measurement of stenosis or reviewing MPRs.
Authors: B B Ertl-Wagner; R Bruening; J Blume; R-T Hoffmann; S Mueller-Schunk; B Snyder; M F Reiser Journal: AJNR Am J Neuroradiol Date: 2006-01 Impact factor: 3.825
Authors: Li Chen; Stephen R Dager; Dennis W W Shaw; Neva M Corrigan; Mahmud Mossa-Basha; Kristi D Pimentel; Natalia M Kleinhans; Patricia K Kuhl; Jenq-Neng Hwang; Chun Yuan Journal: J Neurosci Methods Date: 2020-04-25 Impact factor: 2.390
Authors: Jin Woo Choi; Joon Beom Seo; Kyung-Hyun Do; Sang Il Choi; Whal Lee; Sung Min Ko; Soo Hyun Lee; Jin Seong Lee; Jae-Woo Song; Koun Sik Song; Tae-Hwan Lim Journal: Korean J Radiol Date: 2006 Jan-Mar Impact factor: 3.500