Literature DB >> 96733

Tryptophan uptake by Mycobacterium tuberculosis H37Rv: effect of rifampin and ethambutol.

K S Sundaram, T A Venkitasubramanian.   

Abstract

Uptake of radioactive tryptophan by Mycobacterium tuberculosis H(37)Rv grown in vitro and in vivo was investigated. K(m) values indicated low affinity, and sodium azide inhibited uptake. Rifampin at the minimal inhibitory concentration had no effect, whereas ethambutol inhibited uptake only in the bacilli grown under in vitro conditions. The significance of these results is discussed.

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Year:  1978        PMID： 96733      PMCID： PMC352323          DOI： 10.1128/AAC.13.5.726

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  19 in total

1.  COMPARISON OF CYTOCHROMES IN MYCOBACTERIA GROWN IN VITRO AND IN VIVO.

Authors:  T KUSAKA; R SATO; K SHOJI
Journal:  J Bacteriol       Date:  1964-06       Impact factor: 3.490

2.  COMPARATIVE STUDY OF MYCOBACTERIUM GROWN IN VIVO AND IN VITRO. V. DIFFERENCES IN STAINING PROPERTIES.

Authors:  W SEGAL
Journal:  Am Rev Respir Dis       Date:  1965-02

3.  COMPARATIVE STUDY OF IN VIVO AND IN VITRO GROWN MYCOBACTERIUM TUBERCULOSIS. 3. LIPID COMPOSITION.

Authors:  W SEGAL; W T MILLER
Journal:  Proc Soc Exp Biol Med       Date:  1965-03

4.  Enzymic breakdown of amino acids and related compounds by suspensions of washed mycobacteria.

Authors:  J M Grange
Journal:  J Appl Bacteriol       Date:  1976-12

5.  The assimilation of amino-acids by bacteria; action of inhibitors on the accumulation of free glutamic acid in Staphylococcus aureus and Streptococcus faecalis.

Authors:  E F GALE
Journal:  Biochem J       Date:  1951-03       Impact factor: 3.857

6.  Separation of tuberculin-active proteins from the infected mouse lung tissue.

Authors:  E Kondo; K Kanai
Journal:  Jpn J Med Sci Biol       Date:  1972-08

7.  The uptake of D-glutamic acid by Mycobacterium avium.

Authors:  K Yabu
Journal:  Biochim Biophys Acta       Date:  1967-02-01

8.  Different mechanisms of energy coupling for transport of various amino acids in cells of Mycobacterium phlei.

Authors:  R Prasad; V K Kalra; A F Brodie
Journal:  J Biol Chem       Date:  1976-04-25       Impact factor: 5.157

9.  Effect of phospholipase A on active transport of amino acids with membrane vesicles of Mycobacterium phlei.

Authors:  R Prasad; V K Kalra; A F Brodie
Journal:  J Biol Chem       Date:  1975-05-25       Impact factor: 5.157

10.  Uptake and binding of 14C-ethambutol by tubercle bacilli and the relation of binding to growth inhibition.

Authors:  W H Beggs; N E Auran
Journal:  Antimicrob Agents Chemother       Date:  1972-11       Impact factor: 5.191
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  1 in total

1.  Gut Microbiota Metabolite Indole Propionic Acid Targets Tryptophan Biosynthesis in Mycobacterium tuberculosis.

Authors:  Dereje Abate Negatu; Yoshiyuki Yamada; Yu Xi; Mei Lin Go; Matthew Zimmerman; Uday Ganapathy; Véronique Dartois; Martin Gengenbacher; Thomas Dick
Journal:  mBio       Date:  2019-03-26       Impact factor: 7.867
  1 in total

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