Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 5-Fluoro-2-methyl-N-[4-(5H-pyrrolo[2,1-c]-[1, 4]benzodiazepin-10(11H)-ylcarbonyl)-3-chlorophenyl]benzamide (VPA-985): an orally active arginine vasopressin antagonist with selectivity for V2 receptors.

× No keyword cloud information.

18 in total

1. Characterization of a novel nonpeptide vasopressin V(2)-agonist, OPC-51803, in cells transfected human vasopressin receptor subtypes.

Authors: S Nakamura; Y Yamamura; S Itoh; T Hirano; K Tsujimae; M Aoyama; K Kondo; H Ogawa; T Shinohara; K Kan; Y Tanada; S Teramoto; T Sumida; S Nakayama; K Sekiguchi; T Kambe; G Tsujimoto; T Mori; M Tominaga
Journal: Br J Pharmacol Date: 2000-04 Impact factor: 8.739

Review 2. Pharmacoperones: a new therapeutic approach for diseases caused by misfolded G protein-coupled receptors.

Authors: Alfredo Ulloa-Aguirre; P Michael Conn
Journal: Recent Pat Endocr Metab Immune Drug Discov Date: 2011-01

3. Sustained aquaretic effect of the V2-AVP receptor antagonist, RWJ-351647, in cirrhotic rats with ascites and water retention.

Authors: Josefa Ros; Guillermo Fernández-Varo; Javier Muñoz-Luque; Vicente Arroyo; Juan Rodés; Joseph W Gunnet; Keith T Demarest; Wladimiro Jiménez
Journal: Br J Pharmacol Date: 2005-11 Impact factor: 8.739

5-Fluoro-2-methyl-N-[4-(5H-pyrrolo[2,1-c]-[1, 4]benzodiazepin-10(11H)-ylcarbonyl)-3-chlorophenyl]benzamide (VPA-985): an orally active arginine vasopressin antagonist with selectivity for V2 receptors.

1. Characterization of a novel nonpeptide vasopressin V(2)-agonist, OPC-51803, in cells transfected human vasopressin receptor subtypes.

Review 2. Pharmacoperones: a new therapeutic approach for diseases caused by misfolded G protein-coupled receptors.

3. Sustained aquaretic effect of the V2-AVP receptor antagonist, RWJ-351647, in cirrhotic rats with ascites and water retention.

Review 4. Vaptans for the treatment of hyponatremia.

5. The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors.

6. Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants.

7. 5-Dichloro-acetyl-4-methyl-2,3,4,5-tetra-hydro-1H-1,5-benzodiazepin-2-one hemihydrate.

8. 2-[2-(4-Methoxyphenyl)-2,3-dihydro-1H-1,5-benzodiazepin-4-yl]phenol.

9. 4-Methyl-2-oxo-2,3,4,5-tetra-hydro-1H-1,5-benzodiazepine-5-carbaldehyde.

Review 10. Pharmacology of vasopressin antagonists.