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Literature DB >> 962883

Isolation of (copper, zinc)-thioneins from the livers of copper-injected rats.

Abstract

The mixed copper- and zinc-binding proteins, with mol.wt. of approx. 12000, induced in rat liver after injection of copper were isolated and characterized as metallothioneins. Three separate forms were obtained, with 7-11% total metal in the protein, equivalent to 2.6-1.6 cysteine residues/metal atom.

Entities: Chemical Species

Mesh：

Substances：

Year: 1976 PMID： 962883 PMCID： PMC1163885 DOI： 10.1042/bj1570517

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

12 in total

1. The effect of glutathione on protein sulphydryl groups in rat-liver homogenates.

Authors: P C JOCELYN
Journal: Biochem J Date: 1962-12 Impact factor: 3.857

2. Cuprodoxin.

Authors: R Prinz; U Weser
Journal: FEBS Lett Date: 1975-06-15 Impact factor: 4.124

3. Copper-chelatin: purification and properties of a copper-binding protein from rat liver.

Authors: D R Winge; R Premakumar; R D Wiley; K V Rajagopalan
Journal: Arch Biochem Biophys Date: 1975-09 Impact factor: 4.013

4. Isolation of (copper, zinc-) thioneins from pig liver.

Authors: I Bremner; B W Young
Journal: Biochem J Date: 1976-06-01 Impact factor: 3.857

5. Studies on the appearance of a hepatic copper-binding protein in normal and zinc-deficient rats.

Authors: I Bremner; N T Davies
Journal: Br J Nutr Date: 1976-07 Impact factor: 3.718

Review 6. Heavy metal toxicities.

Authors: I Bremner
Journal: Q Rev Biophys Date: 1974-02 Impact factor: 5.318

7. The effect of copper loading on the distribution of copper in rat liver cytosol.

Authors: L C Bloomer; T L Sourkes
Journal: Biochem Med Date: 1973-08

8. Human hepatic metallothioneins.

Authors: R H Bühler; J H Kägi
Journal: FEBS Lett Date: 1974-02-15 Impact factor: 4.124

9. The induction of metallothionein in rat liver by zinc injection and restriction of food intake.

Authors: I Bremner; N T Davies
Journal: Biochem J Date: 1975-09 Impact factor: 3.857

10. Separation of two forms of rabbit metallothionein by isoelectric focusing.

Authors: G F Nordberg; M Nordberg; M Piscator; O Vesterberg
Journal: Biochem J Date: 1972-02 Impact factor: 3.857

31 in total

1. Evidence for a high molecular weight cytosolic factor that binds brain and liver metallothionein.

Authors: T Gasull; J Hidalgo
Journal: Neurochem Res Date: 1996-08 Impact factor: 3.996

2. A study of the copper-binding proteins in liver and kidney tissue of neonatal normal and mottled mutant mice.

Authors: A E Port; D M Hunt
Journal: Biochem J Date: 1979-12-01 Impact factor: 3.857

3. Control of zinc-thionein synthesis in rat liver.

Authors: K S Squibb; R J Cousins; S L Feldman
Journal: Biochem J Date: 1977-04-15 Impact factor: 3.857

4. Development of a radioimmunoassay for rat liver metallothionein-I and its application to the analysis of rat plasma and kidneys.

Authors: R K Mehra; I Bremner
Journal: Biochem J Date: 1983-08-01 Impact factor: 3.857

9. Partial purification, characterization and translation in vitro of rat liver metallothionein messenger ribonucleic acid.

Authors: R D Andersen; U Weser
Journal: Biochem J Date: 1978-12-01 Impact factor: 3.857

10. Genetic studies on metallothionein synthesis in the mouse: the induction of metallothionein by cadmium in inbred strains.

Authors: D M Hunt; T Mhlanga
Journal: Biochem Genet Date: 1983-06 Impact factor: 1.890