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Literature DB >> 9620

Polynucleotides. XL. Synthesis and properties of poly 2'-azido-2'-deoxyadenylic acid.

Abstract

Poly 2'-azido-2'-deoxyadenylic acid (Poly Az) was synthesized from 2'-azido-2'-deoxyadenosine diphosphate by polynucleotide phosphorylase. Poly (Az) has U.V. absorption properties similar to poly (A) and hypochromicity of 40% at 0.1 M Na+ and neutrality. CD curve also resembled to that of poly (A), but has smaller ellipticity. Titration of poly (Az) with HCl gave a transition at pH 5.5, but exact structure of the acid-form complex was not elucidated. Upon mixing with poly (U), poly (Az) forms a 1:1 and 1:2 complexes having Tm's somewhat higher than that of poly (A)- poly (U) complex in the same condition.

Entities: Chemical Disease Gene

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Year: 1976 PMID： 9620 PMCID： PMC343064 DOI： 10.1093/nar/3.8.2089

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

16 in total

1. [POLYNUCLEOTIDE PHOSPHORYLASE PURIFIED FROM ESCHERICHIA COLI].

Authors: F R WILLIAMS; M GRUNBERG-MANAGO
Journal: Biochim Biophys Acta Date: 1964-07-08

2. The molecular structure of polyadenylic acid.

Authors: A RICH; D R DAVIES; F H CRICK; J D WATSON
Journal: J Mol Biol Date: 1961-02 Impact factor: 5.469

3. Studies on the formation of two- and three-stranded polyribonucleotides.

Authors: G FELSENFELD; A RICH
Journal: Biochim Biophys Acta Date: 1957-12

4. Polynucleotides containing 2'-chloro-2'-deoxyribose.

Authors: J Hobbs; H Sternbach; M Sprinzl; F Eckstein
Journal: Biochemistry Date: 1972-11-07 Impact factor: 3.162

5. Synthesis and properties of poly 2'-fluoro-2'-deoxyuridylic acid.

Authors: B Janik; M P Kotick; T H Kreiser; L F Reverman; R G Sommer; D P Wilson
Journal: Biochem Biophys Res Commun Date: 1972-02-16 Impact factor: 3.575

6. Preparation and stability of the helical form of poly 2'-O-ethyluridylic acid.

Authors: J T Kuśmierek; M Kielanowska; D Shugar
Journal: Biochem Biophys Res Commun Date: 1973-07-17 Impact factor: 3.575

7. Synthesis and characterization of potential interferon inducers. Poly(2'-azido-2'-deoxyuridylic acid).

Authors: P F Torrence; A M Bobst; J A Waters; B Witkop
Journal: Biochemistry Date: 1973-09-25 Impact factor: 3.162

8. Synthesis and properties of poly(2-methyladenylic acid). Formation of a poly(A)-poly(U) complex with Hoogsteen-type hydrogen binding.

Authors: M Ikehara; M Hattori; T Fukui
Journal: Eur J Biochem Date: 1972-12-04

9. Comparative studies on homopolymers of adenylic acid possessing different C-2' substituents of the furanose. Poly(deoxyriboadenylic acid), poly(riboadenylic acid),poly(2'-O-methyladenylic acid), and poly(2'-O-ethyladenylic acid).

Authors: J L Alderfer; I Tazawa; S Tazawa; P Ts'o
Journal: Biochemistry Date: 1974-04-09 Impact factor: 3.162

10. Polynucleotides containing 2'-amino-2'-deoxyribose and 2'-azido-2'-deoxyribose.

Authors: J Hobbs; H Sternbach; M Sprinzl; F Eckstein
Journal: Biochemistry Date: 1973-12-04 Impact factor: 3.162

6 in total

1. Polynucleotides. XLV Synthesis and properties of poly(2'-azido-2'-deoxyinosinic acid).

Authors: T Fukui; N Kakiuchi; M Ikehara
Journal: Nucleic Acids Res Date: 1977-08 Impact factor: 16.971

2. Polynucleotides. LII. Synthesis and properties of poly(2'-deoxy-2'-fluoroadenylic acid).

Authors: M Ikehara; T Fukui; N Kakiuchi
Journal: Nucleic Acids Res Date: 1978-06 Impact factor: 16.971

3. Polynucleotides. XLVI. 1 Synthesis and properties of poly (2'-amino-2'-deoxyadenylic acid).

Authors: M Ikehara; T Fukui; N Kakiuchi
Journal: Nucleic Acids Res Date: 1977-04 Impact factor: 16.971

4. Polynucleotides. L. Synthesis and properties of poly (2'-chloro-2'-deoxyadenylic acid) and poly (2'-bromo-2'-deoxyadenylic acid).

Authors: M Ikehara; T Fukui; N Kakiuchi
Journal: Nucleic Acids Res Date: 1977-12 Impact factor: 16.971

5. Polynucleotides. LVI. Synthesis and properties of poly(2-deoxy-2'-fluoroinosinic acid).

Authors: M Ikehara; N Kakiuchi; T Fukui
Journal: Nucleic Acids Res Date: 1978-09 Impact factor: 16.971

6. Polynucleotides. LVII. Synthesis and properties of poly (2'-chloro-2'-deoxyinosinic acid).

Authors: N Kakiuchi; T Fukui; M Ikehara
Journal: Nucleic Acids Res Date: 1979-06-11 Impact factor: 16.971

6 in total