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Literature DB >> 341084

Polynucleotides. L. Synthesis and properties of poly (2'-chloro-2'-deoxyadenylic acid) and poly (2'-bromo-2'-deoxyadenylic acid).

Abstract

Poly (2'-chloro-2'-deoxyadenylic acid) and poly (2'-bromo-2'-deoxyadenylic acid) were synthesized from the corresponding diphosphates with the aid of polynucleotide phosphorylase from E. coli. UV, CD, acid titration and mixing with poly (U) were investigated. Comparing these properties with those of poly (A) and poly (2'-azido-2'-deoxyadenylic acid), it was found that 2''substituents exert significant effects on the thermal stability of these polynucleotides, though the overall conformational structure was not greatly changed.

Entities: Chemical Species

Mesh：

Substances：

Year: 1977 PMID： 341084 PMCID： PMC343238 DOI： 10.1093/nar/4.12.4249

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

8 in total

1. [POLYNUCLEOTIDE PHOSPHORYLASE PURIFIED FROM ESCHERICHIA COLI].

Authors: F R WILLIAMS; M GRUNBERG-MANAGO
Journal: Biochim Biophys Acta Date: 1964-07-08

2. The molecular structure of polyadenylic acid.

Authors: A RICH; D R DAVIES; F H CRICK; J D WATSON
Journal: J Mol Biol Date: 1961-02 Impact factor: 5.469

3. Polynucleotides. XLV Synthesis and properties of poly(2'-azido-2'-deoxyinosinic acid).

Authors: T Fukui; N Kakiuchi; M Ikehara
Journal: Nucleic Acids Res Date: 1977-08 Impact factor: 16.971

4. Polynucleotides. XL. Synthesis and properties of poly 2'-azido-2'-deoxyadenylic acid.

Authors: M Ikehara; T Fukui; N Kakiuchi
Journal: Nucleic Acids Res Date: 1976-08 Impact factor: 16.971

5. Substrate specificity of ribonuclease from Aspergillus saitoi.

Authors: M Imazawa; M Irie; T Ukita
Journal: J Biochem Date: 1968-11 Impact factor: 3.387

6. Calculation of the optical rotatory dispersion of dinucleoside phosphates.

Authors: C A Bush; I Tinoco
Journal: J Mol Biol Date: 1967-02-14 Impact factor: 5.469

7. Polynucleotides. XLVI. 1 Synthesis and properties of poly (2'-amino-2'-deoxyadenylic acid).

Authors: M Ikehara; T Fukui; N Kakiuchi
Journal: Nucleic Acids Res Date: 1977-04 Impact factor: 16.971

8. Comparative studies on homopolymers of adenylic acid possessing different C-2' substituents of the furanose. Poly(deoxyriboadenylic acid), poly(riboadenylic acid),poly(2'-O-methyladenylic acid), and poly(2'-O-ethyladenylic acid).

Authors: J L Alderfer; I Tazawa; S Tazawa; P Ts'o
Journal: Biochemistry Date: 1974-04-09 Impact factor: 3.162

8 in total

4 in total

Polynucleotides. L. Synthesis and properties of poly (2'-chloro-2'-deoxyadenylic acid) and poly (2'-bromo-2'-deoxyadenylic acid).

1. [POLYNUCLEOTIDE PHOSPHORYLASE PURIFIED FROM ESCHERICHIA COLI].

2. The molecular structure of polyadenylic acid.

3. Polynucleotides. XLV Synthesis and properties of poly(2'-azido-2'-deoxyinosinic acid).

4. Polynucleotides. XL. Synthesis and properties of poly 2'-azido-2'-deoxyadenylic acid.

5. Substrate specificity of ribonuclease from Aspergillus saitoi.

6. Calculation of the optical rotatory dispersion of dinucleoside phosphates.

7. Polynucleotides. XLVI. 1 Synthesis and properties of poly (2'-amino-2'-deoxyadenylic acid).

8. Comparative studies on homopolymers of adenylic acid possessing different C-2' substituents of the furanose. Poly(deoxyriboadenylic acid), poly(riboadenylic acid),poly(2'-O-methyladenylic acid), and poly(2'-O-ethyladenylic acid).

1. Structural requirements of polynucleotides for the activation of (2' - 5')An polymerase and protein kinase.

2. Polynucleotides. LII. Synthesis and properties of poly(2'-deoxy-2'-fluoroadenylic acid).

3. Polynucleotides. LVI. Synthesis and properties of poly(2-deoxy-2'-fluoroinosinic acid).

4. Polynucleotides. LVII. Synthesis and properties of poly (2'-chloro-2'-deoxyinosinic acid).