Literature DB >> 9613830

Interactions of putative heparin-binding domains of basic fibroblast growth factor and its receptor, FGFR-1, with heparin using synthetic peptides.

L Kinsella1, H L Chen, J A Smith, P S Rudland, D G Fernig.   

Abstract

We have examined structure-function relationships that have been proposed to account for the heparin-binding properties of basic fibroblast growth factor and its receptor, FGFR-1, using synthetic peptides, DNA synthesis assays and binding assays in a resonant mirror biosensor. The results suggest that the interaction of FGFR-1 with heparin may not be physiologically relevant and that the site of interaction of the polysaccharide on bFGF is more complex than has been anticipated.

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Year:  1998        PMID： 9613830     DOI： 10.1023/a:1006986104865

Source DB:  PubMed          Journal:  Glycoconj J        ISSN： 0282-0080            Impact factor:   2.916


  18 in total

1.  Receptor- and heparin-binding domains of basic fibroblast growth factor.

Authors:  A Baird; D Schubert; N Ling; R Guillemin
Journal:  Proc Natl Acad Sci U S A       Date:  1988-04       Impact factor: 11.205

2.  A rapid procedure for production of human basic fibroblast growth factor in Escherichia coli cells.

Authors:  Y Ke; M C Wilkinson; D G Fernig; J A Smith; P S Rudland; R Barraclough
Journal:  Biochim Biophys Acta       Date:  1992-07-15

3.  Carboxyl-terminal structure of basic fibroblast growth factor significantly contributes to its affinity for heparin.

Authors:  M Seno; R Sasada; T Kurokawa; K Igarashi
Journal:  Eur J Biochem       Date:  1990-03-10

4.  Three-dimensional structure of human basic fibroblast growth factor.

Authors:  A E Eriksson; L S Cousens; L H Weaver; B W Matthews
Journal:  Proc Natl Acad Sci U S A       Date:  1991-04-15       Impact factor: 11.205

5.  Three-dimensional structure of human basic fibroblast growth factor, a structural homolog of interleukin 1 beta.

Authors:  J D Zhang; L S Cousens; P J Barr; S R Sprang
Journal:  Proc Natl Acad Sci U S A       Date:  1991-04-15       Impact factor: 11.205

6.  The use of high-performance liquid chromatography in the isolation and characterisation of mouse and rat epidermal growth factors and examination of apparent heterogeneity.

Authors:  J A Smith; J Ham; D P Winslow; M J O'Hare; P S Rudland
Journal:  J Chromatogr       Date:  1984-02-10

7.  Crystal structure of basic fibroblast growth factor at 1.6 A resolution.

Authors:  H Ago; Y Kitagawa; A Fujishima; Y Matsuura; Y Katsube
Journal:  J Biochem       Date:  1991-09       Impact factor: 3.387

8.  Rat mammary preadipocytes in culture produce a trophic agent for mammary epithelia-prostaglandin E2.

Authors:  P S Rudland; A C Twiston Davies; S W Tsao
Journal:  J Cell Physiol       Date:  1984-09       Impact factor: 6.384

9.  Specific heparan sulfate saccharides mediate the activity of basic fibroblast growth factor.

Authors:  A Walker; J E Turnbull; J T Gallagher
Journal:  J Biol Chem       Date:  1994-01-14       Impact factor: 5.157

10.  Endothelial heparan sulfate proteoglycans that bind to L-selectin have glucosamine residues with unsubstituted amino groups.

Authors:  K Norgard-Sumnicht; A Varki
Journal:  J Biol Chem       Date:  1995-05-19       Impact factor: 5.157
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  8 in total

1.  Controlled dual delivery of fibroblast growth factor-2 and Interleukin-10 by heparin-based coacervate synergistically enhances ischemic heart repair.

Authors:  William C W Chen; Brandon G Lee; Dae Woo Park; Kyobum Kim; Hunghao Chu; Kang Kim; Johnny Huard; Yadong Wang
Journal:  Biomaterials       Date:  2015-09-02       Impact factor: 12.479

2.  Identification of heparin-binding sites in proteins by selective labeling.

Authors:  Alessandro Ori; Paul Free; José Courty; Mark C Wilkinson; David G Fernig
Journal:  Mol Cell Proteomics       Date:  2009-06-30       Impact factor: 5.911

3.  Fibroblast growth factor-2 binds to small heparin-derived oligosaccharides and stimulates a sustained phosphorylation of p42/44 mitogen-activated protein kinase and proliferation of rat mammary fibroblasts.

Authors:  Maryse Delehedde; Malcolm Lyon; John T Gallagher; Philip S Rudland; David G Fernig
Journal:  Biochem J       Date:  2002-08-15       Impact factor: 3.857

4.  Controlling Affinity Binding with Peptide-Functionalized Poly(ethylene glycol) Hydrogels.

Authors:  Chien-Chi Lin; Kristi S Anseth
Journal:  Adv Funct Mater       Date:  2009-07-24       Impact factor: 18.808

5.  Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificity.

Authors:  Ruoyan Xu; Alessandro Ori; Timothy R Rudd; Katarzyna A Uniewicz; Yassir A Ahmed; Scott E Guimond; Mark A Skidmore; Giuliano Siligardi; Edwin A Yates; David G Fernig
Journal:  J Biol Chem       Date:  2012-09-27       Impact factor: 5.157

Review 6.  Heparan sulfate and heparin interactions with proteins.

Authors:  Maria C Z Meneghetti; Ashley J Hughes; Timothy R Rudd; Helena B Nader; Andrew K Powell; Edwin A Yates; Marcelo A Lima
Journal:  J R Soc Interface       Date:  2015-09-06       Impact factor: 4.118

7.  Evaluating the immunogenicity of heparin and heparin derivatives by measuring their binding to platelet factor 4 using biolayer interferometry.

Authors:  Qingqing Chen; Fei Li; Haoran Wang; Changkai Bu; Feng Shi; Lan Jin; Qunye Zhang; Lianli Chi
Journal:  Front Mol Biosci       Date:  2022-08-26

8.  Cytokines and growth factors cross-link heparan sulfate.

Authors:  Elisa Migliorini; Dhruv Thakar; Jens Kühnle; Rabia Sadir; Douglas P Dyer; Yong Li; Changye Sun; Brian F Volkman; Tracy M Handel; Liliane Coche-Guerente; David G Fernig; Hugues Lortat-Jacob; Ralf P Richter
Journal:  Open Biol       Date:  2015-08       Impact factor: 6.411
  8 in total

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