| Literature DB >> 9577090 |
M C Mingari1, A Moretta, L Moretta.
Abstract
Killer-cell inhibitory Receptors (KIRs) are a new family of major histocompatibility complex (MHC) class I-specific receptors. KIRs allow natural killer cells to identify and lyse self cells that do not express sufficient amounts of MHC class I molecules. Here, Maria Cristina Mingari and colleagues view the expression of KIRs by cytolytic T lymphocytes and their regulation by certain cytokines as a double-edged sword.Entities:
Mesh:
Substances:
Year: 1998 PMID: 9577090 DOI: 10.1016/s0167-5699(97)01236-x
Source DB: PubMed Journal: Immunol Today ISSN: 0167-5699