Literature DB >> 9566634

Chemosensory event-related potentials change with age.

T Hummel1, S Barz, E Pauli, G Kobal.   

Abstract

The study examined age-related changes in the perception of olfactory and trigeminal chemical stimuli using chemosensory event-related potentials (CSERP). Three groups of healthy volunteers, each comprised of 8 men and 8 women, were tested (age ranges 15-34, 35-54, and 55-74 years). Subjects underwent extensive psychological testing focusing on impairments of memory and attention. In addition, odor identification and discrimination ability was evaluated, as well as detection threshold sensitivity for two odorants. Odor discrimination scores exhibited a significant age-related decrease. Significant age-related changes were also observed for CSERP N1P2 and P2 amplitudes, and for the N1 peak latency. The age-related decrease of CSERP amplitudes appeared to follow a different time course for responses to trigeminal and olfactory stimulants.

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Year:  1998        PMID： 9566634     DOI： 10.1016/s0168-5597(97)00074-9

Source DB:  PubMed          Journal:  Electroencephalogr Clin Neurophysiol        ISSN： 0013-4694


  21 in total

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