| Literature DB >> 9557735 |
Abstract
At least eight conserved motifs are visible in the totivirus RNA-dependent RNA polymerase (RDRP). We have systematically altered each of these in the Saccharomyces cerevisiae double-stranded RNA virus ScVL1 by substituting the conserved motifs from a giardiavirus. The results help define the conserved regions of the RDRP involved in polymerase function and those essential for other reasons.Entities:
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Year: 1998 PMID: 9557735 PMCID: PMC109675 DOI: 10.1128/JVI.72.5.4427-4429.1998
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103