Literature DB >> 955013

3-hydroxy-3-methylglutaric acid and experimental atherosclerosis in rats.

S Y Yousufzai, M Siddiqi.   

Abstract

In rats 3-hydroxy-3-methylglutaric acid effectively counteracts the lipemic and atherosclerotic response of massive doses of vitamin D2. It regressed the formation of atheromatous arterial lesions. Furthermore the significant decrease in serum beta-lipoprotein levels on HMG treatment could be due to decrease in VLDL triglyceride and cholesterol levels.

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Year:  1976        PMID： 955013     DOI： 10.1007/BF01933955

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  7 in total

1.  Studies on the hypolipidemic and hypocholesterolemic effect of 3-hydroxy-3-methylglutaric acid in rabbits.

Authors:  A N Yusufi; M Siddiqi
Journal:  Atherosclerosis       Date:  1974 Nov-Dec       Impact factor: 5.162

2.  A simple method for the rapid production of atherosclerosis in rats.

Authors:  R F Altman
Journal:  Experientia       Date:  1973-02-15

3.  3-Hydroxy-3-methylglutaric acid: protective action in experimental atherosclerosis in rabbits.

Authors:  P J Lupien; M Tremblay; Z H Beg
Journal:  Atherosclerosis       Date:  1973 Nov-Dec       Impact factor: 5.162

4.  In vitro and in vivo inhibition of hepatic cholesterol synthesis by 3-hydroxy-3-methylglutaric acid.

Authors:  Z H Beg; P J Lupien
Journal:  Biochim Biophys Acta       Date:  1972-03-23

5.  Effect of 3-hydroxy-3-methylglutaric acid on blood lipids in normal and cholesterol-fed rats.

Authors:  Z H Beg; M Siddiqi
Journal:  Experientia       Date:  1968-08-15

6.  Hypocholesterolemic effect of 3-hydroxy-3-methylglutaric acid.

Authors:  Z H Beg; M Siddiqi
Journal:  Experientia       Date:  1967-05-15

7.  Experimental production of gross atherosclerosis in the rat.

Authors:  S B ANDRUS; L C FILLIOS; G V MANN; F J STARE
Journal:  J Exp Med       Date:  1956-10-01       Impact factor: 14.307
  7 in total
  5 in total

1.  Formation and utilization of 3-hydroxy-3-methylglutarate in liver mitochondria of starved and streptozotocin-diabetic rats.

Authors:  R Dena; M Fabbro; F Rigoni
Journal:  Biochem J       Date:  1978-06-15       Impact factor: 3.857

2.  3-Hydroxy-3-methylglutaric acid and triton-induced hyperlipidemia in rats.

Authors:  S Y Yousufzai; M Siddiqi
Journal:  Experientia       Date:  1976-09-15

3.  Serum and liver lipid responses to 3-hydroxy-3-methylglutaric acid in rats on different carbohydrate diets.

Authors:  S Y Yousufzai; M Siddiqi
Journal:  Lipids       Date:  1977-03       Impact factor: 1.880

4.  Tissue lipid responses to 3-hydroxy-3-methylglutaric acid with different dietary fats.

Authors:  S Y Yousufzai; M Siddiqi
Journal:  Lipids       Date:  1977-03       Impact factor: 1.880

5.  Characterization of the Phytochemical Composition and Bioactivities of Anacyclus maroccanus Ball. and Anacyclus radiatus Loisel Aerial Parts: Preliminary Evidence for the Possible Development of Moroccan Plants.

Authors:  Saida Sissi; Silvia Di Giacomo; Claudio Ferrante; Paola Angelini; Alberto Macone; Anna Maria Giusti; Chiara Toniolo; Annabella Vitalone; Aghraz Abdellah; Mustapha Larhsini; Luigi Menghini; Mohammed Markouk; Gabriela Mazzanti; Antonella Di Sotto
Journal:  Molecules       Date:  2022-01-21       Impact factor: 4.411
  5 in total

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