| Literature DB >> 183980 |
Abstract
3-Hydroxy-3-methylglutaric acid (HMG) significantly decreased cholesterol, triglyceride and phospholipid levels in whole serum, serum beta-lipoproteins and liver of Triton-induced hyperlipidemic rats. Therapeutically 50 mg HMG/kg is equivalent to 200 mg nicotinic acid/kg in lowering all these lipid parameters. HMG may exert its hypolipidemic effect through inhibition of lipoprotein synthesis.Entities:
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Year: 1976 PMID： 183980 DOI： 10.1007/bf01927612
Source DB: PubMed Journal: Experientia ISSN： 0014-4754