Literature DB >> 9529118

Increased leptin expression in mice with bacterial peritonitis is partially regulated by tumor necrosis factor alpha.

A K Moshyedi1, M D Josephs, E K Abdalla, S L Mackay, C K Edwards, E M Copeland, L L Moldawer.   

Abstract

Plasma leptin and ob gene mRNA levels were increased in mice following bacterial peritonitis, and blocking an endogenous tumor necrosis factor alpha (TNF-alpha) response blunted the increase. However, plasma leptin concentrations did not correlate with the associated anorexia. We conclude that leptin expression is under partial regulatory control of TNF-alpha in peritonitis, but the anorexia is not dependent on increased leptin production.

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Year:  1998        PMID： 9529118      PMCID： PMC108125     

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  11 in total

1.  Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

Authors:  P Chomczynski; N Sacchi
Journal:  Anal Biochem       Date:  1987-04       Impact factor: 3.365

2.  Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins.

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Journal:  Am J Physiol       Date:  1989-03

3.  Circulating interleukin 1 and tumor necrosis factor during inflammation.

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Journal:  Am J Physiol       Date:  1987-12

4.  Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters.

Authors:  C Grunfeld; C Zhao; J Fuller; A Pollack; A Moser; J Friedman; K R Feingold
Journal:  J Clin Invest       Date:  1996-05-01       Impact factor: 14.808

5.  Impaired immune and acute-phase responses in interleukin-6-deficient mice.

Authors:  M Kopf; H Baumann; G Freer; M Freudenberg; M Lamers; T Kishimoto; R Zinkernagel; H Bluethmann; G Köhler
Journal:  Nature       Date:  1994-03-24       Impact factor: 49.962

6.  Regulation of food intake and hepatic protein synthesis by recombinant-derived cytokines.

Authors:  L L Moldawer; C Andersson; J Gelin; K G Lundholm
Journal:  Am J Physiol       Date:  1988-03

7.  Positional cloning of the mouse obese gene and its human homologue.

Authors:  Y Zhang; R Proenca; M Maffei; M Barone; L Leopold; J M Friedman
Journal:  Nature       Date:  1994-12-01       Impact factor: 49.962

8.  Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo.

Authors:  K J Van Zee; T Kohno; E Fischer; C S Rock; L L Moldawer; S F Lowry
Journal:  Proc Natl Acad Sci U S A       Date:  1992-06-01       Impact factor: 11.205

9.  Effects of the obese gene product on body weight regulation in ob/ob mice.

Authors:  M A Pelleymounter; M J Cullen; M B Baker; R Hecht; D Winters; T Boone; F Collins
Journal:  Science       Date:  1995-07-28       Impact factor: 47.728

10.  Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia.

Authors:  P Sarraf; R C Frederich; E M Turner; G Ma; N T Jaskowiak; D J Rivet; J S Flier; B B Lowell; D L Fraker; H R Alexander
Journal:  J Exp Med       Date:  1997-01-06       Impact factor: 14.307
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  12 in total

Review 1.  Leptin: at the crossroads of energy balance and systemic inflammation.

Authors:  Alexandre A Steiner; Andrej A Romanovsky
Journal:  Prog Lipid Res       Date:  2006-12-21       Impact factor: 16.195

2.  Ablation of leptin receptor-mediated ERK activation impairs host defense against Gram-negative pneumonia.

Authors:  Peter Mancuso; Martin G Myers; Deepti Goel; Carlos H Serezani; Edmund O'Brien; Jared Goldberg; David M Aronoff; Marc Peters-Golden
Journal:  J Immunol       Date:  2012-06-08       Impact factor: 5.422

3.  Protective role of lycopene against metabolic disorders induced by chronic bisphenol A exposure in rats.

Authors:  Rania Abdelrahman Elgawish; Marwa A El-Beltagy; Rehab M El-Sayed; Aya A Gaber; Heba M A Abdelrazek
Journal:  Environ Sci Pollut Res Int       Date:  2020-01-08       Impact factor: 4.223

4.  Endogenous leptin fluctuates in hepatic ischemia/reperfusion injury and represents a potential therapeutic target.

Authors:  Ji Lin; Xiao-Ning Gao; Guang-Tao Yan; Hui Xue; Xiu-Hua Hao; Lu-Huan Wang
Journal:  World J Gastroenterol       Date:  2010-11-21       Impact factor: 5.742

5.  Leptin improves pulmonary bacterial clearance and survival in ob/ob mice during pneumococcal pneumonia.

Authors:  A Hsu; D M Aronoff; J Phipps; D Goel; P Mancuso
Journal:  Clin Exp Immunol       Date:  2007-09-05       Impact factor: 4.330

6.  Leptin modulates neutrophil phagocytosis of Klebsiella pneumoniae.

Authors:  Sharlene I Moore; Gary B Huffnagle; Gwo-Hsiao Chen; Eric S White; Peter Mancuso
Journal:  Infect Immun       Date:  2003-07       Impact factor: 3.441

Review 7.  Malnutrition and gastrointestinal and respiratory infections in children: a public health problem.

Authors:  Leonor Rodríguez; Elsa Cervantes; Rocío Ortiz
Journal:  Int J Environ Res Public Health       Date:  2011-04-18       Impact factor: 3.390

8.  Leptin in septic arthritis: decreased levels during infection and amelioration of disease activity upon its administration.

Authors:  O H Hultgren; A Tarkowski
Journal:  Arthritis Res       Date:  2001-09-19

9.  Leptin-deficient mice are protected from accelerated nephrotoxic nephritis.

Authors:  Ruth M Tarzi; H Terence Cook; Ian Jackson; Charles D Pusey; Graham M Lord
Journal:  Am J Pathol       Date:  2004-02       Impact factor: 4.307

10.  Effects of Nano-sized Carbon Black on the Lungs of High Fat-diet Induced Overweight Rats.

Authors:  Cheol-Hong Lim; Mingu Kang; Jeong-Hee Han; Hyo-In Yun
Journal:  Environ Health Toxicol       Date:  2013-11-22
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