Literature DB >> 9520599

The DNA revolution in population genetics.

L L Cavalli-Sforza1.   

Abstract

Unprecedental clarity has come to our understanding of genetic variation by the analysis of DNA sequences. It is not surprising that the new DNA technologies are leading to a resurgence of interest in population genetics. In this review, I discuss recent progress and future directions towards reconstructing the history of human populations. There is increasing consensus on a recent 'Out of Africa' origin of modern humans, which explains why the greatest fraction of genetic diversity is found within populations, rather than between them. The comparison of Y chromosome and mitochondrial DNA data shows remarkable sex differences in geographic variation. The analysis of Neanderthal DNA has been a major breakthrough in the study of fossil DNA. Among major hopes for the future are application to polygenic diseases.

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Year:  1998        PMID： 9520599     DOI： 10.1016/s0168-9525(97)01327-9

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  30 in total

1.  dbSNP: a database of single nucleotide polymorphisms.

Authors:  E M Smigielski; K Sirotkin; M Ward; S T Sherry
Journal:  Nucleic Acids Res       Date:  2000-01-01       Impact factor: 16.971

2.  dbSNP: the NCBI database of genetic variation.

Authors:  S T Sherry; M H Ward; M Kholodov; J Baker; L Phan; E M Smigielski; K Sirotkin
Journal:  Nucleic Acids Res       Date:  2001-01-01       Impact factor: 16.971

3.  The distribution of human genetic diversity: a comparison of mitochondrial, autosomal, and Y-chromosome data.

Authors:  L B Jorde; W S Watkins; M J Bamshad; M E Dixon; C E Ricker; M T Seielstad; M A Batzer
Journal:  Am J Hum Genet       Date:  2000-03       Impact factor: 11.025

4.  mtDNA analysis of Nile River Valley populations: A genetic corridor or a barrier to migration?

Authors:  M Krings; A E Salem; K Bauer; H Geisert; A K Malek; L Chaix; C Simon; D Welsby; A Di Rienzo; G Utermann; A Sajantila; S Pääbo; M Stoneking
Journal:  Am J Hum Genet       Date:  1999-04       Impact factor: 11.025

5.  The ambiguous meanings of the racial/ethnic categories routinely used in human genetics research.

Authors:  Linda M Hunt; Mary S Megyesi
Journal:  Soc Sci Med       Date:  2007-10-23       Impact factor: 4.634

6.  Genetic variability of inflammatory genes in the Brazilian population.

Authors:  Marcelo dos Santos; Elaine Stur; Lucas Lima Maia; Lidiane Pignaton Agostini; Gabriela Tonini Peterle; Suzanny Oliveira Mendes; Eloiza Helena Tajara; Marcos Brasilino de Carvalho; Iúri Drumond Louro; Adriana Madeira Álvares Silva-Conforti
Journal:  Genet Test Mol Biomarkers       Date:  2013-08-03

Review 7.  The Chinese human genome diversity project.

Authors:  L L Cavalli-Sforza
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-29       Impact factor: 11.205

Review 8.  Complex genetic origin of Indian populations and its implications.

Authors:  Rakesh Tamang; Lalji Singh; Kumarasamy Thangaraj
Journal:  J Biosci       Date:  2012-11       Impact factor: 1.826

Review 9.  Relevance of connexin deafness (DFNB1) to human evolution.

Authors:  Walter E Nance; Michael J Kearsey
Journal:  Am J Hum Genet       Date:  2004-04-09       Impact factor: 11.025

10.  Distinguishing human ethnic groups by means of sequences from Helicobacter pylori: lessons from Ladakh.

Authors:  Thierry Wirth; Xiaoyan Wang; Bodo Linz; Richard P Novick; J Koji Lum; Martin Blaser; Giovanna Morelli; Daniel Falush; Mark Achtman
Journal:  Proc Natl Acad Sci U S A       Date:  2004-03-29       Impact factor: 11.205
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