Literature DB >> 9519303

Formation and stability of beta-hairpin structures in polypeptides.

F Blanco1, M Ramírez-Alvarado, L Serrano.   

Abstract

Experimental work on peptide models with beta-hairpin structures has provided new insights into the formation and stability of this secondary structure element. Both the turn region and the antiparallel strand residues not only affect the overall stability of the hairpin, but also determine the type of hairpin formed. These results agree reasonably well with those from experimental and statistical analyses of beta-sheet structures in proteins.

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Year:  1998        PMID： 9519303     DOI： 10.1016/s0959-440x(98)80017-1

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN： 0959-440X            Impact factor:   6.809


  38 in total

1.  The turn sequence directs beta-strand alignment in designed beta-hairpins.

Authors:  E de Alba; M Rico; M A Jiménez
Journal:  Protein Sci       Date:  1999-11       Impact factor: 6.725

2.  Molecular dynamics simulations of unfolding and refolding of a beta-hairpin fragment of protein G.

Authors:  V S Pande; D S Rokhsar
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

3.  A molecular dynamics study of the 41-56 beta-hairpin from B1 domain of protein G.

Authors:  D Roccatano; A Amadei; A Di Nola; H J Berendsen
Journal:  Protein Sci       Date:  1999-10       Impact factor: 6.725

4.  Understanding beta-hairpin formation by molecular dynamics simulations of unfolding.

Authors:  J Lee; S Shin
Journal:  Biophys J       Date:  2001-11       Impact factor: 4.033

5.  13C(alpha) and 13C(beta) chemical shifts as a tool to delineate beta-hairpin structures in peptides.

Authors:  C M Santiveri; M Rico; M A Jiménez
Journal:  J Biomol NMR       Date:  2001-04       Impact factor: 2.835

6.  BetaCore, a designed water soluble four-stranded antiparallel beta-sheet protein.

Authors:  Natàlia Carulla; Clare Woodward; George Barany
Journal:  Protein Sci       Date:  2002-06       Impact factor: 6.725

7.  Interplay between hydrophobic cluster and loop propensity in beta-hairpin formation: a mechanistic study.

Authors:  Giorgio Colombo; Giacomo M S De Mori; Danilo Roccatano
Journal:  Protein Sci       Date:  2003-03       Impact factor: 6.725

8.  Surfing on protein folding energy landscapes.

Authors:  Joost W H Schymkowitz; Frederic Rousseau; Luis Serrano
Journal:  Proc Natl Acad Sci U S A       Date:  2002-12-02       Impact factor: 11.205

Review 9.  Combinatorial chemistry of beta-hairpins.

Authors:  M Teresa Pastor; Enrique Pérez-Payá
Journal:  Mol Divers       Date:  2003       Impact factor: 2.943

10.  Modulation of zinc- and cobalt-binding affinities through changes in the stability of the zinc ribbon protein L36.

Authors:  Wenpeng Kou; Harsha S Kolla; Alfonso Ortiz-Acevedo; Donovan C Haines; Matthew Junker; Gregg R Dieckmann
Journal:  J Biol Inorg Chem       Date:  2005-03-04       Impact factor: 3.358
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