Literature DB >> 948742

Multiplication of a human parasite (Leishmania donovani) in phagolysosomes of hamster macrophages in vitro.

K P Chang, D M Dwyer.   

Abstract

Leishmania donovani, the etiological agent of human visceral leishmaniasis, was grown in hamster peritoneal macrophages in vitro. By electron microscopy, using a lysosomal marker, these parasitic protozoa were seen to multiply within host cell phagolysosomes. The survival mechanism of this intracellular parasite is based apparently upon resistance to macrophage lysosomal enzymic digestion.

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Year:  1976        PMID： 948742     DOI： 10.1126/science.948742

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  75 in total

1.  Ligation of Fc receptor of macrophages stimulates protein kinase C and anti-leishmanial activity.

Authors:  D Dasgupta; P Chakraborty; M K Basu
Journal:  Mol Cell Biochem       Date:  2000-06       Impact factor: 3.396

2.  Ca2+ signaling in the transformation of promastigotes to axenic amastigotes of Leishmania donovani.

Authors:  A Prasad; S Kaur; N Malla; N K Ganguly; R C Mahajan
Journal:  Mol Cell Biochem       Date:  2001-08       Impact factor: 3.396

3.  Infection of retinal epithelial cells with L. amazonensis impacts in extracellular matrix proteins.

Authors:  Kátia da Silva Calabrese; Leandro de Souza Silva; Luiz Otávio Pereira Carvalho; Daiana de Jesus Hardoim; Mariana da Silva-Almeida; Renato Arruda Mortara; Celeste da Silva Freitas de Souza
Journal:  Parasitol Res       Date:  2011-04-15       Impact factor: 2.289

4.  Analysis of the Leishmania donovani transcriptome reveals an ordered progression of transient and permanent changes in gene expression during differentiation.

Authors:  A Saxena; T Lahav; N Holland; G Aggarwal; A Anupama; Y Huang; H Volpin; P J Myler; D Zilberstein
Journal:  Mol Biochem Parasitol       Date:  2006-12-12       Impact factor: 1.759

5.  An improved method for detection of Leishmania amastigotes by an antibody probe against the small subunit of leishmanial ribonucleotide reductase.

Authors:  Shu-Ching Chang; Oleg Kuzmenok; Su-Chi Chiang; Sho Tone Lee
Journal:  Parasitol Res       Date:  2004-08-27       Impact factor: 2.289

6.  Comparison of the expression profiles of promastigotes and axenic amastigotes in Leishmania donovani using serial analysis of gene expression.

Authors:  Qiaoli Li; Yangxing Zhao; Bing Ni; Chenjiang Yao; Ying Zhou; Wangjie Xu; Zhaoxia Wang; Zhongdong Qiao
Journal:  Parasitol Res       Date:  2008-06-22       Impact factor: 2.289

Review 7.  Beyond oncology--application of HPMA copolymers in non-cancerous diseases.

Authors:  Xin-Ming Liu; Scott C Miller; Dong Wang
Journal:  Adv Drug Deliv Rev       Date:  2009-11-10       Impact factor: 15.470

8.  Activation of macrophages for destruction of Francisella tularensis: identification of cytokines, effector cells, and effector molecules.

Authors:  A H Fortier; T Polsinelli; S J Green; C A Nacy
Journal:  Infect Immun       Date:  1992-03       Impact factor: 3.441

9.  The Leishmania donovani lipophosphoglycan excludes the vesicular proton-ATPase from phagosomes by impairing the recruitment of synaptotagmin V.

Authors:  Adrien F Vinet; Mitsunori Fukuda; Salvatore J Turco; Albert Descoteaux
Journal:  PLoS Pathog       Date:  2009-10-16       Impact factor: 6.823

10.  Temperature increase prevails over acidification in gene expression modulation of amastigote differentiation in Leishmania infantum.

Authors:  Pedro J Alcolea; Ana Alonso; Manuel J Gómez; Alicia Sánchez-Gorostiaga; Mercedes Moreno-Paz; Eduardo González-Pastor; Alfredo Toraño; Víctor Parro; Vicente Larraga
Journal:  BMC Genomics       Date:  2010-01-14       Impact factor: 3.969
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