| Literature DB >> 9453637 |
D M Rosales-Borjas1, J Díaz-Rivadeneyra, A Doña-Leyva, S A Zambrano-Villa, C Mascaró, A Osuna, L Ortiz-Ortiz.
Abstract
The secretory immune response in humans infected with Giardia lamblia was studied by using saliva samples and a membrane-rich protein fraction. The membrane fraction, studied by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, showed 24 antigen bands, ranging from 170 to 14 kDa. Saliva samples from giardiasis patients showed a heterogeneous response against the membrane fraction when they were assayed by immunoblotting. Among the antigens recognized by patient saliva samples, those of 170, 105, 92, 66, 32, 29, and 14 kDa stood out. These antigens were not recognized by saliva samples from healthy individuals. They may be of importance in future studies of protection from or diagnosis of G. lamblia infections.Entities:
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Year: 1998 PMID: 9453637 PMCID: PMC107966
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441