M S Wolfe1, M Citron, T S Diehl, W Xia, I O Donkor, D J Selkoe. Show Affiliations » 1. Department of Pharmaceutical Sciences, University of Tennessee, Memphis 38163, USA. mwolfe@utmem1.utmem.edu
Abstract
Entities: Chemical Disease
Mesh: See more » Alzheimer Disease/enzymologyAmino Acid SequenceAmyloid Precursor Protein SecretasesAmyloid beta-Peptides/metabolismAmyloid beta-Protein Precursor/metabolismAnimalsAspartic Acid EndopeptidasesCHO CellsCricetinaeEndopeptidases/metabolismHumansKetones/chemical synthesisKetones/chemistryKetones/pharmacologyOligopeptides/chemical synthesisOligopeptides/chemistryOligopeptides/pharmacologyProtease Inhibitors/chemical synthesisProtease Inhibitors/chemistryProtease Inhibitors/pharmacologyRecombinant Proteins/antagonists & inhibitorsSubstrate SpecificityTransfection
Substances: See more » Amyloid beta-PeptidesAmyloid beta-Protein PrecursorKetonesOligopeptidesProtease InhibitorsRecombinant ProteinsAmyloid Precursor Protein SecretasesEndopeptidasesAspartic Acid EndopeptidasesBACE1 protein, human
Year: 1998 PMID: 9438016 DOI: 10.1021/jm970621b
Source DB: PubMed Journal: J Med Chem ISSN: 0022-2623 Impact factor: 7.446