Literature DB >> 11696563

Spotlight on BACE: the secretases as targets for treatment in Alzheimer disease.

C Dingwall1.   

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Year:  2001        PMID： 11696563      PMCID： PMC209454          DOI： 10.1172/JCI14402

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


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  48 in total

1.  Alzheimer's disease. In search of gamma-secretase.

Authors:  J Hardy; A Israël
Journal:  Nature       Date:  1999-04-08       Impact factor: 49.962

2.  Targeting of membrane proteins to endosomes and lysosomes.

Authors:  I V Sandoval; O Bakke
Journal:  Trends Cell Biol       Date:  1994-08       Impact factor: 20.808

Review 3.  Tau protein pathology in neurodegenerative diseases.

Authors:  M G Spillantini; M Goedert
Journal:  Trends Neurosci       Date:  1998-10       Impact factor: 13.837

4.  Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein.

Authors:  S Bodovitz; W L Klein
Journal:  J Biol Chem       Date:  1996-02-23       Impact factor: 5.157

5.  Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells.

Authors:  S Parvathy; I Hussain; E H Karran; A J Turner; N M Hooper
Journal:  Biochemistry       Date:  1999-07-27       Impact factor: 3.162

6.  Characterization of Alzheimer's beta -secretase protein BACE. A pepsin family member with unusual properties.

Authors:  M Haniu; P Denis; Y Young; E A Mendiaz; J Fuller; J O Hui; B D Bennett; S Kahn; S Ross; T Burgess; V Katta; G Rogers; R Vassar; M Citron
Journal:  J Biol Chem       Date:  2000-07-14       Impact factor: 5.157

Review 7.  Genes, models and Alzheimer's disease.

Authors:  P F Chapman; A M Falinska; S G Knevett; M F Ramsay
Journal:  Trends Genet       Date:  2001-05       Impact factor: 11.639

8.  Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities.

Authors:  M Citron; T S Diehl; G Gordon; A L Biere; P Seubert; D J Selkoe
Journal:  Proc Natl Acad Sci U S A       Date:  1996-11-12       Impact factor: 11.205

9.  Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1.

Authors:  Y M Li; M Xu; M T Lai; Q Huang; J L Castro; J DiMuzio-Mower; T Harrison; C Lellis; A Nadin; J G Neduvelil; R B Register; M K Sardana; M S Shearman; A L Smith; X P Shi; K C Yin; J A Shafer; S J Gardell
Journal:  Nature       Date:  2000-06-08       Impact factor: 49.962

10.  Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease.

Authors:  M Goedert; M G Spillantini; R Jakes; D Rutherford; R A Crowther
Journal:  Neuron       Date:  1989-10       Impact factor: 17.173
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  8 in total

1.  Targeted delivery of proteins across the blood-brain barrier.

Authors:  Brian J Spencer; Inder M Verma
Journal:  Proc Natl Acad Sci U S A       Date:  2007-04-26       Impact factor: 11.205

2.  Proteomic analysis of the amyloid precursor protein fragment C99: expression in yeast.

Authors:  Louis J Sparvero; Sarah Patz; Jeffrey L Brodsky; Christina M Coughlan
Journal:  Anal Biochem       Date:  2007-08-10       Impact factor: 3.365

3.  Proteasome activity modulates amyloid toxicity.

Authors:  John Galvin; Elizabeth Curran; Francisco Arteaga; Alicia Goossens; Nicki Aubuchon-Endsley; Michael A McMurray; Jeffrey Moore; Kirk C Hansen; Heidi J Chial; Huntington Potter; Jeffrey L Brodsky; Christina M Coughlan
Journal:  FEMS Yeast Res       Date:  2022-03-09       Impact factor: 2.796

4.  Comparative molecular field analysis and comparative molecular similarity indices analysis of hydroxyethylamine derivatives as selective human BACE-1 inhibitor.

Authors:  Ashish Pandey; Jignesh Mungalpara; C Gopi Mohan
Journal:  Mol Divers       Date:  2009-03-28       Impact factor: 2.943

5.  Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice.

Authors:  Michael T Heneka; Magdalena Sastre; Lucia Dumitrescu-Ozimek; Ilse Dewachter; Jochen Walter; Thomas Klockgether; Fred Van Leuven
Journal:  J Neuroinflammation       Date:  2005-10-07       Impact factor: 8.322

6.  Beta 2-adrenergic receptor activation enhances neurogenesis in Alzheimer's disease mice.

Authors:  Gao-Shang Chai; Yang-Yang Wang; Amina Yasheng; Peng Zhao
Journal:  Neural Regen Res       Date:  2016-10       Impact factor: 5.135

7.  Repurposing food molecules as a potential BACE1 inhibitor for Alzheimer's disease.

Authors:  Nobendu Mukerjee; Anubhab Das; Rahul D Jawarkar; Swastika Maitra; Padmashree Das; Melvin A Castrosanto; Soumyadip Paul; Abdul Samad; Magdi E A Zaki; Sami A Al-Hussain; Vijay H Masand; Mohammad Mehedi Hasan; Syed Nasir Abbas Bukhari; Asma Perveen; Badrah S Alghamdi; Athanasios Alexiou; Mohammad Amjad Kamal; Abhijit Dey; Sumira Malik; Ravindra L Bakal; Adel Mohammad Abuzenadah; Arabinda Ghosh; Ghulam Md Ashraf
Journal:  Front Aging Neurosci       Date:  2022-08-22       Impact factor: 5.702

Review 8.  From Hybrids to New Scaffolds: The Latest Medicinal Chemistry Goals in Multi-target Directed Ligands for Alzheimer's Disease.

Authors:  Jazmín Alarcón-Espósito; Michael Mallea; Julio Rodríguez-Lavado
Journal:  Curr Neuropharmacol       Date:  2021       Impact factor: 7.363
  8 in total

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