Literature DB >> 9433569

Genetic analysis of simulated oligogenic traits in nuclear and extended pedigrees: summary of GAW10 contributions.

E M Wijsman1, C I Amos.   

Abstract

Participants of GAW10 had available simulated data on phenotypic and marker data for 200 replicates of each of two different collections of pedigrees. The simulated phenotype was multivariate and oligogenic, and included a number of complexities. Participants took widely different approaches to analysis. We compare their results to identify analysis approaches and use of the data that had the greatest impact on the conclusions, accuracy of estimates, and power to identify genetic factors.

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Year:  1997        PMID： 9433569     DOI： 10.1002/(SICI)1098-2272(1997)14:6<719::AID-GEPI28>3.0.CO;2-S

Source DB:  PubMed          Journal:  Genet Epidemiol        ISSN： 0741-0395            Impact factor:   2.135


  66 in total

1.  Bayesian mapping of quantitative trait loci under complicated mating designs.

Authors:  N Yi; S Xu
Journal:  Genetics       Date:  2001-04       Impact factor: 4.562

2.  Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. I. Likelihood formulation and simulation results.

Authors:  J T Williams; P Van Eerdewegh; L Almasy; J Blangero
Journal:  Am J Hum Genet       Date:  1999-10       Impact factor: 11.025

3.  Testing the robustness of the likelihood-ratio test in a variance-component quantitative-trait loci-mapping procedure.

Authors:  D B Allison; M C Neale; R Zannolli; N J Schork; C I Amos; J Blangero
Journal:  Am J Hum Genet       Date:  1999-08       Impact factor: 11.025

4.  Absence of significant linkage between phonological coding dyslexia and chromosome 6p23-21.3, as determined by use of quantitative-trait methods: confirmation of qualitative analyses.

Authors:  T L Petryshen; B J Kaplan; M F Liu; L L Field
Journal:  Am J Hum Genet       Date:  2000-02       Impact factor: 11.025

5.  Sampling strategies for model free linkage analyses of quantitative traits: implications for sib pair studies of reading and spelling disabilities to minimize the total study cost.

Authors:  A Ziegler
Journal:  Eur Child Adolesc Psychiatry       Date:  1999       Impact factor: 4.785

6.  Reading disability: evidence for a genetic etiology.

Authors:  J Gayán; R K Olson
Journal:  Eur Child Adolesc Psychiatry       Date:  1999       Impact factor: 4.785

7.  Genetics of event-related brain potentials in response to a semantic priming paradigm in families with a history of alcoholism.

Authors:  L Almasy; B Porjesz; J Blangero; A Goate; H J Edenberg; D B Chorlian; S Kuperman; S J O'Connor; J Rohrbaugh; L O Bauer; T Foroud; J P Rice; T Reich; H Begleiter
Journal:  Am J Hum Genet       Date:  2000-12-01       Impact factor: 11.025

8.  Human pedigree-based quantitative-trait-locus mapping: localization of two genes influencing HDL-cholesterol metabolism.

Authors:  L Almasy; J E Hixson; D L Rainwater; S Cole; J T Williams; M C Mahaney; J L VandeBerg; M P Stern; J W MacCluer; J Blangero
Journal:  Am J Hum Genet       Date:  1999-06       Impact factor: 11.025

9.  Evidence of linkage of HDL level variation to APOC3 in two samples with different ascertainment.

Authors:  France Gagnon; Gail P Jarvik; Arno G Motulsky; Samir S Deeb; John D Brunzell; Ellen M Wijsman
Journal:  Hum Genet       Date:  2003-08-29       Impact factor: 4.132

10.  Genome scan for cognitive trait loci of dyslexia: Rapid naming and rapid switching of letters, numbers, and colors.

Authors:  Kevin B Rubenstein; Wendy H Raskind; Virginia W Berninger; Mark M Matsushita; Ellen M Wijsman
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2014-05-08       Impact factor: 3.568
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