Literature DB >> 9406544

Dimerization of the UmuD' protein in solution and its implications for regulation of SOS mutagenesis.

A E Ferentz, T Opperman, G C Walker, G Wagner.   

Abstract

NMR spectroscopy has been used to determine that the dimerization interface of UmuD' in solution is not the homodimer interface originally inferred from crystallographic data. Instead, it resembles an interface that had been hypothesized to be involved in filamentation.

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Year:  1997        PMID: 9406544     DOI: 10.1038/nsb1297-979

Source DB:  PubMed          Journal:  Nat Struct Biol        ISSN: 1072-8368


  29 in total

1.  umuDC-mediated cold sensitivity is a manifestation of functions of the UmuD(2)C complex involved in a DNA damage checkpoint control.

Authors:  M D Sutton; G C Walker
Journal:  J Bacteriol       Date:  2001-02       Impact factor: 3.490

2.  A model for a umuDC-dependent prokaryotic DNA damage checkpoint.

Authors:  T Opperman; S Murli; B T Smith; G C Walker
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

3.  Posttranslational modification of the umuD-encoded subunit of Escherichia coli DNA polymerase V regulates its interactions with the beta processivity clamp.

Authors:  Mark D Sutton; Issay Narumi; Graham C Walker
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-16       Impact factor: 11.205

4.  Converting a DNA damage checkpoint effector (UmuD2C) into a lesion bypass polymerase (UmuD'2C).

Authors:  A E Ferentz; G C Walker; G Wagner
Journal:  EMBO J       Date:  2001-08-01       Impact factor: 11.598

5.  The preferred substrate for RecA-mediated cleavage of bacteriophage 434 repressor is the DNA-bound dimer.

Authors:  David R Pawlowski; Gerald B Koudelka
Journal:  J Bacteriol       Date:  2004-01       Impact factor: 3.490

6.  Distinct peptide signals in the UmuD and UmuD' subunits of UmuD/D' mediate tethering and substrate processing by the ClpXP protease.

Authors:  Saskia B Neher; Robert T Sauer; Tania A Baker
Journal:  Proc Natl Acad Sci U S A       Date:  2003-10-31       Impact factor: 11.205

7.  Common protein architecture and binding sites in proteases utilizing a Ser/Lys dyad mechanism.

Authors:  M Paetzel; N C Strynadka
Journal:  Protein Sci       Date:  1999-11       Impact factor: 6.725

8.  A constitutively expressed, truncated umuDC operon regulates the recA-dependent DNA damage induction of a gene in Acinetobacter baylyi strain ADP1.

Authors:  Janelle M Hare; Sara N Perkins; Leslie A Gregg-Jolly
Journal:  Appl Environ Microbiol       Date:  2006-06       Impact factor: 4.792

9.  The bacteriophage 434 repressor dimer preferentially undergoes autoproteolysis by an intramolecular mechanism.

Authors:  Barbara C McCabe; David R Pawlowski; Gerald B Koudelka
Journal:  J Bacteriol       Date:  2005-08       Impact factor: 3.490

10.  Novel Escherichia coli umuD' mutants: structure-function insights into SOS mutagenesis.

Authors:  M McLenigan; T S Peat; E G Frank; J P McDonald; M Gonzalez; A S Levine; W A Hendrickson; R Woodgate
Journal:  J Bacteriol       Date:  1998-09       Impact factor: 3.490

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