OBJECTIVE: To evaluate stereotactic transcranial magnetic stimulation (TMS) as a tool for presurgical functional mapping of human motor cortex. METHODS: Transcranial magnetic stimulation using a frameless stereotactic system was performed in two patients with tumors near the central sulcus. TMS motor function maps were plotted on the patients' three-dimensional volumetric magnetic resonance imaging data and compared with direct electrical cortical stimulation at surgery with the patient under local anesthesia. RESULTS: Stereotactic TMS was well tolerated by both patients and was consistent with known somatotopic representation of human motor cortex. The results demonstrated a good correlation between the TMS and electrical cortical stimulation maps, with all TMS responses eliciting more than 75% of the maximum motor evoked potential falling within 1 cm of the electrical cortical stimulation site. CONCLUSIONS: Our findings indicate that stereotactic TMS is feasible and can provide accurate noninvasive localization of cortical motor function. It may prove to be a useful method for presurgical planning.
OBJECTIVE: To evaluate stereotactic transcranial magnetic stimulation (TMS) as a tool for presurgical functional mapping of human motor cortex. METHODS: Transcranial magnetic stimulation using a frameless stereotactic system was performed in two patients with tumors near the central sulcus. TMS motor function maps were plotted on the patients' three-dimensional volumetric magnetic resonance imaging data and compared with direct electrical cortical stimulation at surgery with the patient under local anesthesia. RESULTS: Stereotactic TMS was well tolerated by both patients and was consistent with known somatotopic representation of human motor cortex. The results demonstrated a good correlation between the TMS and electrical cortical stimulation maps, with all TMS responses eliciting more than 75% of the maximum motor evoked potential falling within 1 cm of the electrical cortical stimulation site. CONCLUSIONS: Our findings indicate that stereotactic TMS is feasible and can provide accurate noninvasive localization of cortical motor function. It may prove to be a useful method for presurgical planning.
Authors: T Krings; M Schreckenberger; V Rohde; H Foltys; U Spetzger; O Sabri; M H Reinges; S Kemeny; P T Meyer; W Möller-Hartmann; M Korinth; J M Gilsbach; U Buell; A Thron Journal: J Neurol Neurosurg Psychiatry Date: 2001-12 Impact factor: 10.154
Authors: L D Gugino; J R Romero; L Aglio; D Titone; M Ramirez; A Pascual-Leone; E Grimson; N Weisenfeld; R Kikinis; M E Shenton Journal: Clin Neurophysiol Date: 2001-10 Impact factor: 3.708
Authors: T Krings; M H Reinges; S Erberich; S Kemeny; V Rohde; U Spetzger; M Korinth; K Willmes; J M Gilsbach; A Thron Journal: J Neurol Neurosurg Psychiatry Date: 2001-06 Impact factor: 10.154
Authors: Jack L Lancaster; Shalini Narayana; Dennis Wenzel; James Luckemeyer; John Roby; Peter Fox Journal: Hum Brain Mapp Date: 2004-08 Impact factor: 5.038
Authors: Henri Hannula; Shelley Ylioja; Antti Pertovaara; Antti Korvenoja; Jarmo Ruohonen; Risto J Ilmoniemi; Synnöve Carlson Journal: Hum Brain Mapp Date: 2005-10 Impact factor: 5.038