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Literature DB >> 938466

The formation of alanine from amino acids in diaphragm muscle of the rat.

Abstract

Alanine production and pyruvate content of the isolated rat hemidiaphragm are increased by isoleucine or glutamate. These results support the hypothesis that amino acids are converted into pyruvate before oxidation and that some pyruvate is transaminated to alanine, which is released from the muscle.

Entities: Chemical Species

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Year: 1976 PMID： 938466 PMCID： PMC1172735 DOI： 10.1042/bj1540555

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

13 in total

1. OXIDATION OF AMINO ACIDS BY ISOLATED RAT DIAPHRAGM AND THE INFLUENCE OF INSULIN.

Authors: K L MANCHESTER
Journal: Biochim Biophys Acta Date: 1965-04-12

2. Regulation of glucose uptake by muscle. 1. The effects of insulin, anaerobiosis and cell poisons on the uptake of glucose and release of potassium by isolated rat diaphragm.

Authors: P J RANDLE; G H SMITH
Journal: Biochem J Date: 1958-11 Impact factor: 3.857

Review 3. Protein turnover and amino acid metabolism in the regulation of gluconeogenesis.

Authors: P Felig; J Wahren
Journal: Fed Proc Date: 1974-04

4. Origin and possible significance of alanine production by skeletal muscle.

Authors: R Odessey; E A Khairallah; A L Goldberg
Journal: J Biol Chem Date: 1974-12-10 Impact factor: 5.157

5. The formation of glutamine and alanine in skeletal muscle.

Authors: N B Ruderman; M Berger
Journal: J Biol Chem Date: 1974-09-10 Impact factor: 5.157

6. Regulation of glucose uptake by muscle. 9. Effects of fatty acids and ketone bodies, and of alloxan-diabetes and starvation, on pyruvate metabolism and on lactate-pyruvate and L-glycerol 3-phosphate-dihydroxyacetone phosphate concentration ratios in rat heart and rat diaphragm muscles.

Authors: P B Garland; E A Newsholme; P J Randle
Journal: Biochem J Date: 1964-12 Impact factor: 3.857

7. Oxidation of amino acids by red and white muscle fiber groups.

Authors: C H Beatty; S Curtis; M K Young; R M Bocek
Journal: Am J Physiol Date: 1974-08

8. The regulation of glycolysis in perfused locust flight muscle.

Authors: W C Ford; D J Candy
Journal: Biochem J Date: 1972-12 Impact factor: 3.857

9. The activities of pyruvate carboxylase, phosphoenolpyruvate carboxylase and fructose diphosphatase in muscles from vertebrates and invertebrates.

Authors: B Crabtree; S J Higgins; E A Newsholme
Journal: Biochem J Date: 1972-11 Impact factor: 3.857

10. The activities of fructose 1,6-diphosphatase, phosphofructokinase and phosphoenolpyruvate carboxykinase in white muscle and red muscle.

Authors: L H Opie; E A Newsholme
Journal: Biochem J Date: 1967-05 Impact factor: 3.857

30 in total

7. Branched-chain amino acid metabolism and alanine formation in rat muscles in vitro. Mitochondrial-cytosolic interrelationships.

Authors: K Snell; D A Duff
Journal: Biochem J Date: 1985-02-01 Impact factor: 3.857

The formation of alanine from amino acids in diaphragm muscle of the rat.

1. OXIDATION OF AMINO ACIDS BY ISOLATED RAT DIAPHRAGM AND THE INFLUENCE OF INSULIN.

2. Regulation of glucose uptake by muscle. 1. The effects of insulin, anaerobiosis and cell poisons on the uptake of glucose and release of potassium by isolated rat diaphragm.

Review 3. Protein turnover and amino acid metabolism in the regulation of gluconeogenesis.

4. Origin and possible significance of alanine production by skeletal muscle.

5. The formation of glutamine and alanine in skeletal muscle.

6. Regulation of glucose uptake by muscle. 9. Effects of fatty acids and ketone bodies, and of alloxan-diabetes and starvation, on pyruvate metabolism and on lactate-pyruvate and L-glycerol 3-phosphate-dihydroxyacetone phosphate concentration ratios in rat heart and rat diaphragm muscles.

7. Oxidation of amino acids by red and white muscle fiber groups.

8. The regulation of glycolysis in perfused locust flight muscle.

9. The activities of pyruvate carboxylase, phosphoenolpyruvate carboxylase and fructose diphosphatase in muscles from vertebrates and invertebrates.

10. The activities of fructose 1,6-diphosphatase, phosphofructokinase and phosphoenolpyruvate carboxykinase in white muscle and red muscle.

1. Carcass glycogen as a potential source of glucose during short-term starvation.

2. The role of phosphoenolpyruvate carboxykinase in amino acid metabolism in muscle.

3. Carnitine deficiency: clinical, morphological, and biochemical observations in a fatal case.

4. The effect of ketone bodies on alanine and glutamine metabolism in isolated skeletal muscle from the fasted chick.

5. Amino acid metabolism by perfused rat hindquarter. Effects of insulin, leucine and 2-chloro-4-methylvalerate.

6. Interference by branched-chain amino acids in the assay of alanine with alanine dehydrogenase.

7. Branched-chain amino acid metabolism and alanine formation in rat muscles in vitro. Mitochondrial-cytosolic interrelationships.

8. Alterations in alanine metabolism in diabetic dogs during short-term treatment with an artificial B cell.

9. Metabolism and transport of glutamine and glucose in vascularly perfused small intestine rat.

10. Effect of starvation on the turnover and metabolic response to leucine.