Literature DB >> 9384569

Competition--a common motif for the imprinting mechanism?

D P Barlow1.   

Abstract

Imprinted genes, in contrast to the majority of mammalian genes, are able to restrict expression to one of the two parental alleles in somatic diploid cells. Although the silent allele of an imprinted gene appears to be transcriptionally repressed, it often bears little other resemblance to normal genes in an inactive state. The key to the imprinting mechanism may be a form of parental-specific expression-competition between cis-linked genes and not parental-specific expression versus repression. Thus, the imprinting mechanism may be better understood if the chromosomal region containing imprinted genes is viewed as 'active' on both parental chromosomes.

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Year:  1997        PMID: 9384569      PMCID: PMC1170293          DOI: 10.1093/emboj/16.23.6899

Source DB:  PubMed          Journal:  EMBO J        ISSN: 0261-4189            Impact factor:   11.598


  55 in total

1.  Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element.

Authors:  M A Ripoche; C Kress; F Poirier; L Dandolo
Journal:  Genes Dev       Date:  1997-06-15       Impact factor: 11.361

2.  Developmental regulation of beta-globin gene switching.

Authors:  O R Choi; J D Engel
Journal:  Cell       Date:  1988-10-07       Impact factor: 41.582

3.  Allele-specific replication timing of imprinted gene regions.

Authors:  D Kitsberg; S Selig; M Brandeis; I Simon; I Keshet; D J Driscoll; R D Nicholls; H Cedar
Journal:  Nature       Date:  1993-07-29       Impact factor: 49.962

4.  An imprinted mouse transcript homologous to the human imprinted in Prader-Willi syndrome (IPW) gene.

Authors:  R Wevrick; U Francke
Journal:  Hum Mol Genet       Date:  1997-02       Impact factor: 6.150

5.  Parental imprinting of the mouse H19 gene.

Authors:  M S Bartolomei; S Zemel; S M Tilghman
Journal:  Nature       Date:  1991-05-09       Impact factor: 49.962

6.  Aberrant imprinting of the insulin-like growth factor II receptor gene in Wilms' tumor.

Authors:  Y Q Xu; P Grundy; C Polychronakos
Journal:  Oncogene       Date:  1997-03-06       Impact factor: 9.867

7.  The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus.

Authors:  D P Barlow; R Stöger; B G Herrmann; K Saito; N Schweifer
Journal:  Nature       Date:  1991-01-03       Impact factor: 49.962

8.  Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene.

Authors:  H Sasaki; P A Jones; J R Chaillet; A C Ferguson-Smith; S C Barton; W Reik; M A Surani
Journal:  Genes Dev       Date:  1992-10       Impact factor: 11.361

9.  Promoter-specific imprinting of the human insulin-like growth factor-II gene.

Authors:  T H Vu; A R Hoffman
Journal:  Nature       Date:  1994-10-20       Impact factor: 49.962

10.  Deletions of a differentially methylated CpG island at the SNRPN gene define a putative imprinting control region.

Authors:  J S Sutcliffe; M Nakao; S Christian; K H Orstavik; N Tommerup; D H Ledbetter; A L Beaudet
Journal:  Nat Genet       Date:  1994-09       Impact factor: 38.330

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  25 in total

1.  Establishment and maintenance of DNA methylation patterns in mouse Ndn: implications for maintenance of imprinting in target genes of the imprinting center.

Authors:  M L Hanel; R Wevrick
Journal:  Mol Cell Biol       Date:  2001-04       Impact factor: 4.272

Review 2.  Beckwith-Wiedemann syndrome: imprinting in clusters revisited.

Authors:  E R Maher; W Reik
Journal:  J Clin Invest       Date:  2000-02       Impact factor: 14.808

Review 3.  Genomic imprinting: implications for human disease.

Authors:  J G Falls; D J Pulford; A A Wylie; R L Jirtle
Journal:  Am J Pathol       Date:  1999-03       Impact factor: 4.307

Review 4.  RNA-directed DNA methylation.

Authors:  M Wassenegger
Journal:  Plant Mol Biol       Date:  2000-06       Impact factor: 4.076

5.  The Dlk1 and Gtl2 genes are linked and reciprocally imprinted.

Authors:  J V Schmidt; P G Matteson; B K Jones; X J Guan; S M Tilghman
Journal:  Genes Dev       Date:  2000-08-15       Impact factor: 11.361

6.  p57(KIP2) is not mutated in hepatoblastoma but shows increased transcriptional activity in a comparative analysis of the three imprinted genes p57(KIP2), IGF2, and H19.

Authors:  W Hartmann; A Waha; A Koch; C G Goodyer; S Albrecht; D von Schweinitz; T Pietsch
Journal:  Am J Pathol       Date:  2000-10       Impact factor: 4.307

7.  The imprinted Air ncRNA is an atypical RNAPII transcript that evades splicing and escapes nuclear export.

Authors:  Christine I M Seidl; Stefan H Stricker; Denise P Barlow
Journal:  EMBO J       Date:  2006-07-27       Impact factor: 11.598

8.  Investigation of elements sufficient to imprint the mouse Air promoter.

Authors:  F Sleutels; D P Barlow
Journal:  Mol Cell Biol       Date:  2001-08       Impact factor: 4.272

Review 9.  Monoallelic gene expression in mammals.

Authors:  Irina S Zakharova; Alexander I Shevchenko; Suren M Zakian
Journal:  Chromosoma       Date:  2009-02-26       Impact factor: 4.316

10.  Multiple mechanisms regulate imprinting of the mouse distal chromosome 7 gene cluster.

Authors:  T Caspary; M A Cleary; C C Baker; X J Guan; S M Tilghman
Journal:  Mol Cell Biol       Date:  1998-06       Impact factor: 4.272

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