Literature DB >> 938120

Suppression of gastrin release and gastric secretion by gastric inhibitory polypeptide (GIP) and vasoactive intestinal polypeptide (VIP).

H V Villar, H R Fender, P L Rayford, S R Bloom, N I Ramus, J C Thompson.   

Abstract

Five dogs prepared with Heidenhain pouches received infusions of saline, GIP and VIP before and after a standard meat meal. Blood samples were obtained under basal conditions and at subsequent intervals for measurement of gastrin, insulin, GIP and VIP by radioimmunoassay. GIP and VIP infusions had no effect on basal levels of gastrin. GIP and VIP (in common with secretin and glucagon) were found to suppress food-stimulated release of gastrin and gastrin-stimulated acid secretion from the Heidenhain pouch. Insulin levels were significantly elevated during GIP and VIP infusions. Food released GIP (and perhaps VIP.

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Year:  1976        PMID： 938120      PMCID： PMC1344314          DOI： 10.1097/00000658-197607000-00016

Source DB:  PubMed          Journal:  Ann Surg        ISSN： 0003-4932            Impact factor:   12.969


  19 in total

1.  The effect of glucagon on gastric secretion in man.

Authors:  D A DREILING; H D JANOWITZ
Journal:  Gastroenterology       Date:  1959-05       Impact factor: 22.682

2.  Inhibitory effect of pancreatic secretin on gastric secretion.

Authors:  H B GREENLEE; E H LONGHI; J D GUERRERO; T S NELSEN; A L EL-BEDRI; L R DRAGSTEDT
Journal:  Am J Physiol       Date:  1957-09

3.  Effect of glucagon on gastric secretion.

Authors:  R M ROBINSON; K HARRIS; C J HLAD; B EISEMAN
Journal:  Proc Soc Exp Biol Med       Date:  1957-11

4.  Inhibition of histamine-, pentagastrin-, and insulin-stimulated canine gastric secretion by pure "gastric inhibitory polypeptide".

Authors:  R A Pederson; J C Brown
Journal:  Gastroenterology       Date:  1972-03       Impact factor: 22.682

5.  Vasoactive intestinal peptide and watery-diarrhoea syndrome.

Authors:  S R Bloom; J M Polak; A G Pearse
Journal:  Lancet       Date:  1973-07-07       Impact factor: 79.321

6.  Effect of glucagon on circulating gastrin.

Authors:  H D Becker; D D Reeder; J C Thompson
Journal:  Gastroenterology       Date:  1973-07       Impact factor: 22.682

7.  Radioimmunoassay for gastric inhibitory polypeptide.

Authors:  M Kuzio; J R Dryburgh; K M Malloy; J C Brown
Journal:  Gastroenterology       Date:  1974-03       Impact factor: 22.682

8.  Hyperglycemic and glycogenolytic effects of vasoactive intestinal polypeptide.

Authors:  C Kerins; S I Said
Journal:  Proc Soc Exp Biol Med       Date:  1973-03

9.  Effect of secretin on circulating gastrin.

Authors:  J C Thompson; D D Reeder; H H Bunchman; H D Becker; E N Brandt
Journal:  Ann Surg       Date:  1972-09       Impact factor: 12.969

10.  Effect of Glucagon on Gastric Secretion in Man.

Authors:  A G Melrose
Journal:  Gut       Date:  1960-06       Impact factor: 23.059
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  14 in total

1.  Acid and endocrine responses to meals varying in pH in normal and duodenal ulcer subjects.

Authors:  J C Thompson; J S Swierczek
Journal:  Ann Surg       Date:  1977-10       Impact factor: 12.969

2.  Effect of fat on meal-stimulated gastric and pancreatic secretion.

Authors:  O L Llanos; J S Swierczek; T A Miller; S I Said; P L Rayford; J C Thompson
Journal:  World J Surg       Date:  1977-07       Impact factor: 3.352

3.  Radioimmunoassay study of hepatic clearance and disappearance half-time of somatostatin and vasoactive intestinal peptide in dogs.

Authors:  J A Chayvialle; P L Rayford; J C Thompson
Journal:  Gut       Date:  1981-09       Impact factor: 23.059

4.  Effect of duodenal osmolality on gastrin and secretin release and on gastric and pancreatic secretion.

Authors:  R K Teichmann; J S Swierczek; P L Rayford; J C Thompson
Journal:  World J Surg       Date:  1979-09-20       Impact factor: 3.352

5.  ECL-cell histamine mobilization in conscious rats: effects of locally applied regulatory peptides, candidate neurotransmitters and inflammatory mediators.

Authors:  P Norlén; M Bernsand; T Konagaya; R Håkanson
Journal:  Br J Pharmacol       Date:  2001-12       Impact factor: 8.739

6.  Vasoactive intestinal polypeptide (VIP) as a mediator of the watery diarrhea syndrome.

Authors:  S I Said
Journal:  World J Surg       Date:  1979-09-20       Impact factor: 3.352

7.  Glucose-dependent insulinotropic peptide: structure of the precursor and tissue-specific expression in rat.

Authors:  C C Tseng; L A Jarboe; S B Landau; E K Williams; M M Wolfe
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-01       Impact factor: 11.205

8.  Mannitol and glucose: effects on gastric acid secretion and endogenous gastric inhibitory polypeptide (GIP).

Authors:  T M O'Dorisio; J T Spaeth; E W Martin; K R Sirinek; N R Thomford; E L Mazzaferri; S Cataland
Journal:  Am J Dig Dis       Date:  1978-12

9.  Effect of intracerebroventricular injection of vasoactive intestinal polypeptide on systemic blood pressure and pancreatic and gastric secretions in the rat.

Authors:  K Mizuta; M Moriga; H Narusawa; H Uchino; M Aono
Journal:  Gastroenterol Jpn       Date:  1986-02

10.  Changes in duodenal enteroendocrine cells in patients with irritable bowel syndrome following dietary guidance.

Authors:  Tarek Mazzawi; Magdy El-Salhy
Journal:  Exp Biol Med (Maywood)       Date:  2017-03-17
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