Literature DB >> 18668731

Effect of Glucagon on Gastric Secretion in Man.

A G Melrose.   

Abstract

Glucagon suppresses gastric acid secretion in normal subjects and in ulcer patients. It has no inhibitory effect while the stomach is under maximal histamine stimulation. The mechanism of action is discussed, and experiments are described which indicate that glucagon is unlikely to be of value in the treatment of peptic ulcer.

Entities:  

Year:  1960        PMID： 18668731      PMCID： PMC1413207          DOI： 10.1136/gut.1.2.142

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  15 in total

1.  Malabsorption and jejunal ulceration due to gastric hypersecretion with pancreatic islet-cell hyperplasia.

Authors:  W H SUMMERSKILL
Journal:  Lancet       Date:  1959-01-17       Impact factor: 79.321

2.  The pancreas: insulin and glucagon.

Authors:  F D LUKENS
Journal:  Annu Rev Physiol       Date:  1959       Impact factor: 19.318

3.  The effect of glucagon on gastric secretion in man.

Authors:  D A DREILING; H D JANOWITZ
Journal:  Gastroenterology       Date:  1959-05       Impact factor: 22.682

4.  The nature and function of the alpha cells of the pancreas; their possible role in the production of glucagon.

Authors:  W KORP; P M LECOMPTE
Journal:  Diabetes       Date:  1955 Sep-Oct       Impact factor: 9.461

5.  Studies on the relationship of glucagon (HGF) to blood pepsinogen concentrations.

Authors:  A S EARLE; G F CAHILL; C S HOAR
Journal:  Ann Surg       Date:  1957-07       Impact factor: 12.969

6.  Multiple endocrine tumors and peptic ulcer.

Authors:  E R FISHER; R H FLANDREAU
Journal:  Gastroenterology       Date:  1957-06       Impact factor: 22.682

7.  Recent developments in glucagon research.

Authors:  H ELRICK; A STAUB; H MASKE
Journal:  N Engl J Med       Date:  1957-04-18       Impact factor: 91.245

8.  Effect of glucagon on gastric secretion.

Authors:  R M ROBINSON; K HARRIS; C J HLAD; B EISEMAN
Journal:  Proc Soc Exp Biol Med       Date:  1957-11

9.  Relation of glucagon to A cells of the pancreas.

Authors:  S A BENCOSME; J FREI
Journal:  Proc Soc Exp Biol Med       Date:  1956-04

10.  Primary peptic ulcerations of the jejunum associated with islet cell tumors of the pancreas.

Authors:  R M ZOLLINGER; E H ELLISON
Journal:  Ann Surg       Date:  1955-10       Impact factor: 12.969
View more
  7 in total

1.  GASTRIC MUCOSAL STRUCTURE AND FUNCTION AFTER VAGOTOMY.

Authors:  A G MELROSE; R I RUSSELL; A DICK
Journal:  Gut       Date:  1964-12       Impact factor: 23.059

2.  Changes in liver, pancreatic and stomach morphology following chronic glucagon administration in guinea-pigs.

Authors:  J M CAMERON; A G MELROSE
Journal:  Br J Exp Pathol       Date:  1962-08

3.  Factors in the pathogenesis of peptic ulcer. The present basis of treatment.

Authors:  J E LENNARD-JONES
Journal:  Postgrad Med J       Date:  1960-12       Impact factor: 2.401

4.  Suppression of gastrin release and gastric secretion by gastric inhibitory polypeptide (GIP) and vasoactive intestinal polypeptide (VIP).

Authors:  H V Villar; H R Fender; P L Rayford; S R Bloom; N I Ramus; J C Thompson
Journal:  Ann Surg       Date:  1976-07       Impact factor: 12.969

5.  [Gastric secretion analysis in the Zollinger-Ellison syndrome].

Authors:  R Ottenjann; H Peters
Journal:  Klin Wochenschr       Date:  1968-08-15

6.  Neurotensin induced inhibition of gastric acid secretion in duodenal ulcer patients before and after parietal cell vagotomy.

Authors:  P S Olsen; J H Pedersen; P Kirkegaard; H Been; F Stadil; J Fahrenkrug; J Christiansen
Journal:  Gut       Date:  1984-05       Impact factor: 23.059

7.  Prostaglandins E and F in endocrine diarrheagenic syndromes.

Authors:  B M Jaffe; S Condon
Journal:  Ann Surg       Date:  1976-10       Impact factor: 12.969
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.